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VT-1161

National Institutes of Health

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PyridinesTetrazoles

Papers overview

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2019
2019
An Investigation into Clinically Relevant Determinants of Azole Resistance in Candida albicans
"Candida albicans is a commensal organism commonly colonizing the human gut and skin. As an opportunistic pathogen, it can cause… 
2017
2017
Efficacy of the Investigational Antifungal VT-1161 in Treating Naturally Occurring 1 Coccidioidomycosis in Dogs 2 3 Running Title : VT-1161 in Dogs with Cocci 4 5
17 Coccidioidomycosis can be a chronic, systemic fungal infection requiring long-term to 18 lifetime medication. Thus there is a… 
2016
2016
VT-1129 and VT-1161 have in vitro activity against Candida isolates from patients with chronic mucocutaneous candidiasis
2016
2016
Investigational CYP51 Inhibitors VT-1161 and VT-1129 Show Strong Activity In Vitro Against Candida krusei
2015
2015
VT-1161 Emerges as Potential Treatment for Acute Vulvovaginal Candidiasis
2012
2012
The Clinical Antifungal Agent VT-1161 is Orally Efficacious in a Murine Model of C. albicans Vaginitis
Murine vaginitis model. A condition of pseudoestrus is required to obtain a persistent vaginal yeast infection in rodents. Mice… 
2011
2011
The Clinical Antifungal VT-1161 is a Highly Potent Inhibitor of Candida albicans, but not Human, CYP51
2010
2010
Interscience Conference on Antimicrobial Agents and Chemotherapy - 50th Annual Meeting - Research on Promising New Agents: Part 2.
  • K. Walker
  • IDrugs : the investigational drugs journal
  • 2010
  • Corpus ID: 28249953
The 50th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), held in Boston, included topics… 
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