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VPS8 gene

Known as: FLJ32099, VPS8, VPS8, CORVET complex subunit 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt
Two related multisubunit tethering complexes promote endolysosomal trafficking in all eukaryotes: Rab5-binding CORVET that was… Expand
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2018
2018
Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions
Recycling endosomes maintain plasma membrane homeostasis and are important for cell polarity, migration, and cytokinesis. Yet… Expand
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2018
2018
A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis
Apicomplexans use the endolysosomal system for the biogenesis of their secretory organelles, namely, micronemes, rhoptries, and… Expand
2017
2017
VPS18 recruits VPS41 to the human HOPS complex via a RING–RING interaction
Eukaryotic cells use conserved multisubunit membrane tethering complexes, including CORVET (class C core vacuole/endosome… Expand
2016
2016
MiniCORVET is a Vps8-containing early endosomal tether in Drosophila
Yeast studies identified two heterohexameric tethering complexes, which consist of 4 shared (Vps11, Vps16, Vps18 and Vps33) and 2… Expand
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Highly Cited
2012
Highly Cited
2012
SnapShot: Mammalian Rab Proteins in Endocytic Trafficking
RAB4A,B,C (CCV, EE, RE)Endocytic recycling ZFYVE20- VPS45, RABEP1, RUFY1, GRIPAP1, AKAP10, RAB11FIP1, CD2APRAB5A,B,C EE fusion… Expand
2010
2010
Mapping of Vps21 and HOPS Binding Sites in Vps8 and Effect of Binding Site Mutants on Endocytic Trafficking
ABSTRACT Vps8 is a subunit of the CORVET tethering complex, which is involved in early-to-late endosome fusion. Here, we examine… Expand
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2005
2005
Charakterisierung der endosomalen Proteintransportfunktion Vps8 der Hefe Saccharomyces cerevisiae
Es wurde die Rolle von Vps8, eines Klasse D vps Proteins, bei Transportprozessen im endosomalen Weg der Knospenhefe Saccharomyces… Expand
2003
2003
Overexpression of genes involved in vesicular trafficking to the vacuole defends against lethal effects of oxidative damage.
Anticancer bleomycins and structurally-related analogs are oxidative agents that mimic ionizing radiation in many of their… Expand
Highly Cited
2000
Highly Cited
2000
Pep3p/Pep5p complex: a putative docking factor at multiple steps of vesicular transport to the vacuole of Saccharomyces cerevisiae.
Pep3p and Pep5p are known to be necessary for trafficking of hydrolase precursors to the vacuole and for vacuolar biogenesis… Expand
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