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VPS16 gene

Known as: VACUOLAR PROTEIN SORTING 16, YEAST, HOMOLOG OF, VPS16, VPS16, CORVET/HOPS core subunit 
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Loss‐of‐Function Variants in HOPS Complex Genes VPS16 and VPS41 Cause Early Onset Dystonia Associated with Lysosomal Abnormalities
The majority of people with suspected genetic dystonia remain undiagnosed after maximal investigation, implying that a number of… 
Highly Cited
2018
Highly Cited
2018
Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis
Significance Plant vacuoles play unique roles such as storage and coloring, in addition to lysosomal/vacuolar functions shared by… 
2017
2017
Genetic studies on the physiological role of CORVET in Aspergillus nidulans
Abstract CORVET and HOPS are protein complexes mediating the maturation of early endosomes (EEs) into late endosomes (LEs… 
2016
2016
Homozygous mutation of VPS16 gene is responsible for an autosomal recessive adolescent-onset primary dystonia
Dystonia is a neurological movement disorder that is clinically and genetically heterogeneous. Herein, we report the… 
2016
2016
Can the cargo control the car? Mitochondrial DNA as a stimulator of TLR9-mediated autophagosome–lysosome fusion
Can the cargo control the car? Mitochondrial DNA as a stimulator of TLR9-mediated autophagosome–lysosome fusion 
Highly Cited
2015
Highly Cited
2015
Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes
The mammalian homotypic fusion and vacuole protein sorting (HOPS) complex is comprised of six subunits: VPS11, VPS16, VPS18… 
Highly Cited
2013
Highly Cited
2013
Structural basis of Vps33A recruitment to the human HOPS complex by Vps16
The multisubunit homotypic fusion and vacuole protein sorting (HOPS) membrane-tethering complex is required for late endosome… 
Highly Cited
2013
Highly Cited
2013
Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Intracellular membrane fusion requires the regulated assembly of SNARE (soluble N-ethylmaleimide-sensitive factor (NSF… 
2011
2011
An in vivo RNAi approach to study gene function in hematopoiesis
Hamatopoiese beschreibt den entwicklungbiologischen Vorgang der Differenzierung hamatopoetischer Stammzellen zu den… 
Highly Cited
1993
Highly Cited
1993
The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast.
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