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VP025

 
National Institutes of Health

Papers overview

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2009
2009
The deficit in long-term potentiation induced by chronic administration of amyloid-β is attenuated by treatment of rats with a novel phospholipid-based drug formulation, VP025
Amyloid-beta (Abeta) peptides, the primary component of the amyloid plaques in Alzheimer's disease (AD), exert profound effects… Expand
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2009
2009
A Novel Phospholipid-Based Drug Formulation, VP025, Modulates Age- and LPS-Induced Microglial Activity in the Rat
Background: A common change that occurs with age in the central nervous system is an increase in microglial-associated… Expand
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2008
2008
Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease.
Administration of VP025 (Vasogen Inc.), a novel drug formulation based on phospholipid nanoparticles incorporating… Expand
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2008
2008
Treatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: Implications for Parkinson’s disease
Failure of the ubiquitin-proteasome system to degrade abnormal proteins may underlie the accumulation of alpha-synuclein and… Expand
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2008
2008
Analysis of the effects of amyloid-beta in rat brain : effect of treatment with a novel anti-inflammatory agent VP025
 
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