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VER 155008

Known as: VER-155008, VER155008 
National Institutes of Health

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Broader (1)

Purine Nucleosides

Papers overview

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Highly Cited
2018
Highly Cited
2018
Gold nanorods together with HSP inhibitor-VER-155008 micelles for colon cancer mild-temperature photothermal therapy
2018
2018
Heat shock protein 70 suppresses neuroinflammation induced by α-synuclein in astrocytes
Highly Cited
2017
Highly Cited
2017
Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation
ABSTRACT Paramyxoviral RNAs are synthesized by a viral RNA-dependent RNA polymerase (RdRp) consisting of the large (L) protein… 
2017
2017
Lipopolysaccharide and heat stress impair the estradiol biosynthesis in granulosa cells via increase of HSP70 and inhibition of smad3 phosphorylation and nuclear translocation.
2016
2016
Elucidation of the Cellular Interactome of Ebola Virus Nucleoprotein and Identification of Therapeutic Targets.
Ebola virus (EBOV) infection results in severe disease and in some cases lethal hemorrhagic fever. The infection is directed by… 
Highly Cited
2014
Highly Cited
2014
VER-155008, a small molecule inhibitor of HSP70 with potent anti-cancer activity on lung cancer cell lines
Lung cancer is the most common malignancy and exhibits significant morbidity and mortality worldwide. Among all lung cancer… 
Review
2013
Review
2013
The HSP70 family and cancer.
The HSP70 family of heat shock proteins consists of molecular chaperones of approximately 70kDa in size that serve critical roles… 
Highly Cited
2013
Highly Cited
2013
Functional Analysis of Hsp70 Inhibitors
The molecular chaperones of the Hsp70 family have been recognized as targets for anti-cancer therapy. Since several paralogs of… 
Highly Cited
2012
Highly Cited
2012
The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury
Highly Cited
2010
Highly Cited
2010
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
PurposeThe anti-apoptotic function of the 70 kDa family of heat shock proteins and their role in cancer is well documented. Dual… 
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