Skip to search formSkip to main contentSkip to account menu

VCAN gene

Known as: CSPG2, CHONDROITIN SULFATE PROTEOGLYCAN CORE PROTEIN, CARTILAGE, VERSICAN 
This gene is involved in both cell adhesion and proteoglycan metabolism.
National Institutes of Health

Related topics

Related topics

10 relations
Carbohydrate MetabolismCell AdhesionCell MovementCell-Matrix Junction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Versican-Derived Matrikines Regulate Batf3–Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer
Colorectal cancer originates within immunologically complex microenvironments. To date, the benefits of immunotherapy have been… 
Highly Cited
2009
Highly Cited
2009
Understanding Haemophilus parasuis infection in porcine spleen through a transcriptomics approach
BackgroundHaemophilus parasuis (HPS) is an important swine pathogen that causes Glässer's disease, which is characterized by… 
Highly Cited
2005
Highly Cited
2005
HNF4α reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma
Hepatocyte nuclear factor 4α (HNF4α) is a tissue-specific transcription factor known to regulate a large number of genes in… 
Highly Cited
2005
Highly Cited
2005
Identification of a novel splice site mutation of the CSPG2 gene in a Japanese family with Wagner syndrome.
PURPOSE To investigate the genetic basis and clinical variability of Wagner syndrome, a rare, dominantly inherited… 
Highly Cited
2004
Highly Cited
2004
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma
BackgroundAstrocytoma is a common aggressive intracranial tumor and presents a formidable challenge in the clinic. Association of… 
Highly Cited
2004
Highly Cited
2004
Gene Expression Profiling of Differentially Expressed Genes in Granulosa Cells of Bovine Dominant Follicles Using Suppression Subtractive Hybridization1
Abstract Development of antral follicles beyond 3 to 4 mm in cattle appears as a wave pattern that occurs two to three times… 
Highly Cited
2003
Highly Cited
2003
Methylation profiling of twenty four genes and the concordant methylation behaviours of nineteen genes that may contribute to hepatocellular carcinogenesis
ABSTRACTTo determine the possible role of the epigenetic mechanisms in carcinogenesis of the hepatocellular carcinoma, we… 
Highly Cited
2002
Highly Cited
2002
Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53
TP53 does not fully comply with the Knudson model [Knudson, A. G., Jr. (1971) Proc. Natl. Acad. Sci. USA 68, 820–823] in that a… 
Highly Cited
2001
Highly Cited
2001
Accelerated age-related CpG island methylation in ulcerative colitis.
CpG island hypermethylation is a mechanism of gene silencing that can be usurped by neoplastic cells to inactivate undesirable… 
Highly Cited
1992
Highly Cited
1992
Mapping of the versican proteoglycan gene (CSPG2) to the long arm of human chromosome 5 (5q12-5q14).
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)