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VAS203

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2016
0120092016

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Review
2016
Review
2016
Pharmacologic Neuroprotection for Functional Outcomes After Traumatic Brain Injury: A Systematic Review of the Clinical Literature.
INTRODUCTION Traumatic brain injury (TBI) is a major cause of death and disability worldwide. The deleterious effects of… (More)
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2015
2015
Endothelial nitric oxide synthase mediates arteriolar vasodilatation after traumatic brain injury in mice.
Brain edema and increased cerebral blood volume (CBV) contribute to intracranial hypertension and hence to unfavorable outcome… (More)
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2014
2014
Nitric oxide synthase inhibition with the antipterin VAS203 improves outcome in moderate and severe traumatic brain injury: a placebo-controlled randomized Phase IIa trial (NOSTRA).
Traumatic brain injury (TBI) is an important cause of death and disability. Safety and pharmacodynamics of 4-amino… (More)
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2009
2009
The novel nitric oxide synthase inhibitor 4-amino-tetrahydro-L-biopterine prevents brain edema formation and intracranial hypertension following traumatic brain injury in mice.
Brain edema formation, resulting in increased intracranial pressure (ICP), is one of the most deleterious consequences of… (More)
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