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Uterine leiomyosarcoma

Known as: leiomyosarcoma, uterine, Leiomyosarcoma of the Uterus, Leiomyosarcoma of the Uterine Body 
An aggressive malignant smooth muscle neoplasm, arising from the uterine corpus. It is characterized by a proliferation of neoplastic spindle cells.
National Institutes of Health

Related topics

Related topics

25 relations
Body of uterusConnective Tissue CellsConnective and Soft TissueEpithelial Cells

Broader (1)

leiomyosarcoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
A phase 2 study of temsirolimus (CCI‐779) in patients with soft tissue sarcomas
The primary goal of this trial was to evaluate the confirmed response rate of temsirolimus (CCI‐779), a mammalian target of… 
2007
2007
A phase II trial of thalidomide in patients with refractory leiomyosarcoma of the uterus and correlation with biomarkers of angiogenesis: a gynecologic oncology group study.
2002
2002
Trimetrexate in the treatment of recurrent or advanced leiomyosarcoma of the uterus: a phase II study of the Gynecologic Oncology Group.
OBJECTIVE This study was conducted to determine the objective response of trimetrexate in patients with advanced or recurrent… 
Review
1999
Review
1999
Management of Uterine Leiomyosarcoma in Australia
Summary: Uterine leiomyosarcoma is an uncommon malignancy for which the management varies widely between individual… 
1999
1999
Frequent occurrence of loss of heterozygosity among tumor suppressor genes in uterine leiomyosarcoma.
OBJECTIVE Leiomyosarcoma of the uterus is a rare smooth muscle tumor; it is extremely malignant and the rates of local recurrence… 
Highly Cited
1998
Highly Cited
1998
Reduced expression of calponin h1 in leiomyosarcoma of the uterus.
To determine the genetic differences between various smooth muscle tumors of the uterus, the expression of calponin h1… 
Highly Cited
1998
Highly Cited
1998
Leiomyosarcoma of the uterus: A clinicopathologic, DNA flow cytometric, p53, and mdm-2 analysis of 49 cases.
AIM The authors analyzed in a retrospective manner the prognostic significance of p53 and mdm-2 expression, DNA ploidy, S-phase… 
1996
1996
Immunohistochemistry (Ki-67 and p53) as a tool in determining malignancy in smooth muscle neoplasms (exemplified by a myxoid leiomyosarcoma of the uterus).
Smooth muscle tumours of the uterus at times represent a problem as it may be difficult to distinguish between benign and… 
1990
1990
Complex karyotypic changes, including rearrangements of 12q13 and 14q24, in two leiomyosarcomas.
1989
1989
Electrochemical Treatment of Cancer. I: Variable Response to Anodic and Cathodic Fields
Percutaneous placement of an intraneoplasmic electrode in pulmonary metastases of three patients with extrathoracic primary… 
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