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USP46 gene

Known as: UBIQUITIN-SPECIFIC PEPTIDASE 46, USP46, FLJ12552 
National Institutes of Health

Related topics

Related topics

1 relation
ubiquitin-specific protease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers.
2018
2018
The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival
Metastatic castration resistant prostate cancer is one of the main causes of male cancer associated deaths worldwide. Development… 
2018
2018
Global transcriptome analysis to identify critical genes involved in the pathology of osteoarthritis
Objectives The aim of this study was to identify key pathological genes in osteoarthritis (OA). Methods We searched and… 
Review
2017
Review
2017
Function of the Deubiquitinating Enzyme USP46 in the Nervous System and Its Regulation by WD40-Repeat Proteins
Posttranslational modification of proteins by ubiquitin regulates synapse development and synaptic transmission. Much progress… 
Highly Cited
2015
Highly Cited
2015
The deubiquitinating enzyme USP46 regulates AMPA receptor ubiquitination and trafficking
Alpha‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPARs) are the primary mediators for inter‐neuronal… 
2014
2014
E1-Mediated Recruitment of a UAF1-USP Deubiquitinase Complex Facilitates Human Papillomavirus DNA Replication
ABSTRACT The human papillomavirus (HPV) E1 helicase promotes viral DNA replication through its DNA unwinding activity and… 
Highly Cited
2012
Highly Cited
2012
The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer
PH domain leucine-rich-repeats protein phosphatase (PHLPP) is a family of Ser/Thr protein phosphatases that serve as tumor… 
2011
2011
Lysine 92 Amino Acid Residue of USP46, a Gene Associated with ‘Behavioral Despair’ in Mice, Influences the Deubiquitinating Enzyme Activity
Deubiquitinating enzymes (DUBs) regulate diverse cellular functions by their activity of cleaving ubiquitin from specific protein… 
Highly Cited
2010
Highly Cited
2010
WDR20 Regulates Activity of the USP12·UAF1 Deubiquitinating Enzyme Complex*
The UAF1 (Usp1-associated factor 1) protein binds and stimulates three deubiquitinating enzymes: USP1, USP12, and USP46. Although… 
Highly Cited
2009
Highly Cited
2009
Usp46 is a quantitative trait gene regulating mouse immobile behavior in the tail suspension and forced swimming tests
The tail suspension test (TST) and forced swimming test (FST) are widely used for assessing antidepressant activity and… 
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