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USP39 gene

Known as: UBIQUITIN-SPECIFIC PROTEASE 39, snRNP assembly defective 1 homolog (S.cerevisiae), ubiquitin specific peptidase 39 
 
National Institutes of Health

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USP34 geneubiquitin-specific protease

Papers overview

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2019
2019
USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.
The serine/threonine kinase, CHK2 (checkpoint kinase 2), is a key mediator in DNA damage response and a tumor suppressor, which… Expand
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2019
2019
USP39 promotes ovarian cancer malignant phenotypes and carboplatin chemoresistance.
Ubiquitin‑specific protease 39 (USP39), as one of the deubiquitinating enzymes (DUBs), exhibits aberrant an expression and has… Expand
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2017
2017
USP39 regulates the growth of SMMC-7721 cells via FoxM1.
The present study investigated ubiquitin specific peptidase 39 (USP39) gene knockdown on SMMC-7721 cells in vitro and in vivo… Expand
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2016
2016
Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma
The spliceosome machinery composed of multimeric protein complexes guides precursor messenger RNAs (mRNAs) (pre-mRNAs) splicing… Expand
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2016
2016
Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation
Castration resistance is a serious problem facing clinical treatment of prostate cancer (PCa). The underlying molecular… Expand
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2015
2015
Lentivirus mediated silencing of Ubiquitin Specific Peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro
BackgroundUbiquitin Specific Peptidase 39 (USP39) is a 65 kDa SR-related protein involved in RNA splicing. Previous studies… Expand
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2012
2012
DNA Degradation of Genetically Modified Cottonseed Meal During Feed Processing
The effects of dry heating, wet heating, and extrusion on the degradation of DNA in cottonseed meal (CSM) were studied using… Expand
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2011
2011
Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion
Loss of retinoblastoma (Rb) tumor suppressor function is associated with human malignancies. Molecular and genetic mechanisms… Expand
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2011
2011
Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain
USP4 is a member of the ubiquitin-specific protease (USP) family of deubiquitinating enzymes that has a role in spliceosome… Expand
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2008
2008
Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B.
Accurate chromosome segregation relies on the mitotic spindle checkpoint. This checkpoint acts to restrict ubiquitin ligase… Expand
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