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UPK3A gene

Known as: UPK3A, UPIII, UPIIIA 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2018
02419932018

Papers overview

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2006
2006
Mutations in Uroplakin IIIA are a rare cause of renal hypodysplasia in humans.
BACKGROUND Renal hypodysplasia, characterized by a decrease in nephron number, small overall kidney size, and maldeveloped renal… (More)
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2005
2005
Uroplakin III is not a major candidate gene for primary vesicoureteral reflux
Vesicoureteral reflux (VUR) is the retrograde flow of urine from the bladder into the ureter and towards the kidneys. VUR is the… (More)
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Highly Cited
2004
Highly Cited
2004
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
The apical surface of mouse urothelium is covered by two-dimensional crystals (plaques) of uroplakin (UP) particles. To study… (More)
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2004
2004
No pathogenic mutations in the uroplakin III gene of 25 patients with primary vesicoureteral reflux.
PURPOSE The uroplakin III (UPIII) knockout mouse provides a good model for human primary vesicoureteral reflux (VUR). Since to… (More)
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2003
2003
Uroplakin gene expression in normal human tissues and locally advanced bladder cancer.
The uroplakins are widely regarded as urothelium-specific markers of terminal urothelial cytodifferentiation. This study… (More)
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Highly Cited
2002
Highly Cited
2002
Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability.
Although water, small nonelectrolytes, and gases are freely permeable through most biological membranes, apical membranes of… (More)
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Highly Cited
2001
Highly Cited
2001
Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition.
The apical surfaces of urothelial cells are almost entirely covered with plaques consisting of crystalline, hexagonal arrays of… (More)
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Highly Cited
2000
Highly Cited
2000
Ablation of Uroplakin III Gene Results in Small Urothelial Plaques, Urothelial Leakage, and Vesicoureteral Reflux
Urothelium synthesizes a group of integral membrane proteins called uroplakins, which form two-dimensional crystals (urothelial… (More)
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Highly Cited
1998
Highly Cited
1998
Uroplakin gene expression by normal and neoplastic human urothelium.
cDNA sequences for human uroplakins UPIa, UPIb, UPII, and UPIII were cloned and used to investigate uroplakin transcription by… (More)
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Highly Cited
1995
Highly Cited
1995
Selective interactions of UPIa and UPIb, two members of the transmembrane 4 superfamily, with distinct single transmembrane-domained proteins in differentiated urothelial cells.
The transmembrane 4 (TM4) superfamily contains many important leukocyte differentiation-related surface proteins including CD9… (More)
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