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UNC5C gene

Known as: UNC5C, unc-5 netrin receptor C, UNC5H3 
National Institutes of Health

Related topics

Related topics

2 relations
UNC5B geneUNC5C protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Whole-Exome Sequencing of Muscle-Invasive Bladder Cancer Identifies Recurrent Mutations of UNC5C and Prognostic Importance of DNA Repair Gene Mutations on Survival
Purpose: Because of suboptimal outcomes in muscle-invasive bladder cancer even with multimodality therapy, determination of… 
Highly Cited
2009
Highly Cited
2009
Aberrant methylation of the UNC5C gene is frequently detected in advanced colorectal cancer.
BACKGROUND UNC5C, one of the Netrin-1 receptors, belongs to the functional dependence receptor family, members of which share the… 
Highly Cited
2008
Highly Cited
2008
NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors.
BACKGROUND & AIMS Netrin-1 was recently proposed to play a crucial role during colorectal tumorigenesis by regulating apoptosis… 
2008
2008
The RHOX5 Homeodomain Protein Mediates Transcriptional Repression of the Netrin-1 Receptor Gene Unc5c*
The X-linked mouse Rhox gene cluster contains more than 30 homeobox genes that are candidates to regulate multiple steps in male… 
Highly Cited
2006
Highly Cited
2006
Motor Axon Guidance of the Mammalian Trochlear and Phrenic Nerves: Dependence on the Netrin Receptor Unc5c and Modifier Loci
Netrin signaling is important to guide migrating neurons and axons in many systems. Experiments with vertebrate CNS explants… 
Highly Cited
2004
Highly Cited
2004
Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation
Netrin and its receptors Unc5 and deleted in colorectal carcinoma (DCC) regulate axon guidance and cell migration. We defined… 
Highly Cited
2003
Highly Cited
2003
UNC5H1 Induces Apoptosis via Its Juxtamembrane Region through an Interaction with NRAGE*
The UNC5Hs are axon guidance receptors that mediate netrin-1-dependent chemorepulsion, and dependence receptors that mediate… 
Highly Cited
2003
Highly Cited
2003
The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment
The three mammalian receptors UNC5H1, UNC5H2, and UNC5H3 (also named UNC5A, UNC5B, and UNC5C in human) that belong to the family… 
Highly Cited
2002
Highly Cited
2002
Dissection of the Cellular and Molecular Events that Position Cerebellar Purkinje Cells: A Study of the math1Null-Mutant Mouse
Granule cell precursors in the external germinal layer (EGL) of the cerebellum have been proposed to be a major player in the… 
Highly Cited
1998
Highly Cited
1998
Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary.
Mutation of the Unc5h3 (formally known as rcm) gene has important consequences on neuronal migration during cerebellar… 
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