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Adenosine Receptor Type 2A (A2AAR) plays a role in important processes, such as anti-inflammatory ones. In this way, the present… Expand BACKGROUND
Adenosine is an endogenous purine nucleoside, which mediates a variety of important biological processes and diseases… Expand The importance of binding site plasticity in protein–ligand interactions is well-recognized, and so are the difficulties in… Expand Prediction of pharmacokinetic (PK) profile for inhaled drugs in humans provides valuable information to aid toxicology safety… Expand Changes associated with conformationally selective agonist binding shed light on G protein–coupled receptor activation… Expand Highlight presented by Maria P. Abbracchio
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC… Expand The broad spectrum anti-inflammatory actions of adenosine A2A receptor agonists are well described. The wide distribution of this… Expand