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UHRF1BP1 gene

Known as: UHRF1BP1, UHRF1 binding protein 1, ICBP90 
National Institutes of Health

Related topics

Related topics

1 relation
Chromosomes, Human, Pair 6

Papers overview

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Highly Cited
2009
Highly Cited
2009
The multi-domain protein Np95 connects DNA methylation and histone modification
DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell… 
Highly Cited
2008
Highly Cited
2008
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
DNA methylation of CpG dinucleotides is an important epigenetic modification of mammalian genomes and is essential for the… 
Highly Cited
2008
Highly Cited
2008
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1
Epigenetic inheritance in mammals is characterized by high-fidelity replication of CpG methylation patterns during development… 
Highly Cited
2007
Highly Cited
2007
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
Epigenetic inheritance in mammals relies in part on robust propagation of DNA methylation patterns throughout development. We… 
Highly Cited
2007
Highly Cited
2007
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
DNA methyltransferase (cytosine-5) 1 (Dnmt1) is the principal enzyme responsible for maintenance of CpG methylation and is… 
Highly Cited
2007
Highly Cited
2007
ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation
ABSTRACT Methylation of histone H3 on lysine 9 is critical for diverse biological processes including transcriptional repression… 
Highly Cited
2005
Highly Cited
2005
The retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycle
The retinoblastoma protein (pRB) is encoded by the RB1 gene whose promoter contains several putative binding sites for ICBP90… 
Highly Cited
2004
Highly Cited
2004
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
ICBP90, inverted CCAAT box-binding protein of 90 kDa, has been reported as a regulator of topoisomerase IIα expression. We… 
Highly Cited
2004
Highly Cited
2004
Down‐regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1‐dependent DNA‐damage checkpoint signals contributes to cell cycle arrest at G1/S transition
Checkpoints, which monitor DNA damage and regulate cell cycle progression, ensure genomic integrity and prevent the propagation… 
Highly Cited
2000
Highly Cited
2000
ICBP90, a novel human CCAAT binding protein, involved in the regulation of topoisomerase IIalpha expression.
The one-hybrid system with an inverted CCAAT box as the DNA target sequence was used to identify proteins acting on key DNA… 
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