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UGT1A1 wt Allele

Known as: UDPGT 1-1, UDP glycosyltransferase gene 1, GNT1 
Human UGT1A1 wild-type allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP… 
National Institutes of Health

Papers overview

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2017
2017
Abnormalities in liver function are described in HIV-1-infected patients treated with atazanavir (ATV), an HIV-1 protease… 
2016
2016
UDP-glucuronosyltransferase (UGT) is an enzyme that catalyses a major phase II reaction in drug metabolism. Glucuronidation… 
2016
2016
Sunitinib (SUN) is a multi‐targeted tyrosine kinase inhibitor that was recently approved for the treatment of gastrointestinal… 
2015
2015
Chemoresistance remains a major impediment in cancer therapy. Although major progress has been made in understanding the… 
2014
2014
  • K. Chiba
  • Drug metabolism and pharmacokinetics
  • 2014
  • Corpus ID: 19753717
The aim of preclinical studies is to evaluate the safety and pharmacological effect of new drug entities through in vitro and in… 
2014
2014
Resistance to chemotherapy is a major problem facing cancer treatment. Understanding the molecular basis for drug resistance has… 
2002
2002
In humans, orally administered phenytoin, 5,5-diphenylhydantoin, is mainly excreted as 5-(4'-hydroxyphenyl)-5-phenylhydantoin (4… 
1999
1999
BACKGROUND AND OBJECTIVE The pathogenesis of the hyperbilirubinemia present in approximately 30% of neonates affected by glucose…