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UGT1A1 wt Allele
Known as:
UDPGT 1-1
, UDP glycosyltransferase gene 1
, GNT1
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Human UGT1A1 wild-type allele is located in the vicinity of 2q37 and is approximately 13 kb in length. This allele, which encodes UDP…
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National Institutes of Health
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Related topics
Related topics
13 relations
2q37
Estrogen Metabolic Process
Homo sapiens
Pentose and Glucuronate Interconversions Pathway
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Broader (1)
UGT1A5 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pharmacogenetics-based optimisation of atazanavir treatment: potential role of new genetic predictors
F. S. Falvella
,
E. Ricci
,
+7 authors
A. Riva
Drug Metabolism and Personalized Therapy
2017
Corpus ID: 5483077
Abnormalities in liver function are described in HIV-1-infected patients treated with atazanavir (ATV), an HIV-1 protease…
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2016
2016
Expression of UGT1A subfamily in rat brain.
Y. Sakakibara
,
M. Katoh
,
+4 authors
M. Nadai
Biopharmaceutics & drug disposition
2016
Corpus ID: 7839641
UDP-glucuronosyltransferase (UGT) is an enzyme that catalyses a major phase II reaction in drug metabolism. Glucuronidation…
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2016
2016
Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic‐Metabolizing Enzymes and Transporters in Rat Liver and Kidneys
H. Korashy
,
M. Ansari
,
+5 authors
Bader A. Moraished
Basic & Clinical Pharmacology & Toxicology
2016
Corpus ID: 28077486
Sunitinib (SUN) is a multi‐targeted tyrosine kinase inhibitor that was recently approved for the treatment of gastrointestinal…
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2016
2016
Comparative liver accumulation of dioxin-like compounds in sheep and cattle: Possible role of AhR-mediated xenobiotic metabolizing enzymes.
F. Girolami
,
V. Spalenza
,
+4 authors
Carlo Nebbia
Science of the Total Environment
2016
Corpus ID: 4095026
2015
2015
Sonic Hedgehog factor Gli1: As good as resistant
H. Zahreddine
,
B. Culjkovic-Kraljacic
,
K. Borden
Molecular & Cellular Oncology
2015
Corpus ID: 13789956
Chemoresistance remains a major impediment in cancer therapy. Although major progress has been made in understanding the…
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2014
2014
Perspective of humanized mouse models for assessing PK/PD and toxic profile of drug candidates in preclinical study.
K. Chiba
Drug Metabolism and Pharmacokinetics
2014
Corpus ID: 19753717
The aim of preclinical studies is to evaluate the safety and pharmacological effect of new drug entities through in vitro and in…
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2014
2014
Inducible drug modification: A new form of resistance
B. Culjkovic-Kraljacic
,
H. Zahreddine
,
K. Borden
Cell Cycle
2014
Corpus ID: 33938830
Resistance to chemotherapy is a major problem facing cancer treatment. Understanding the molecular basis for drug resistance has…
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