UBE2O gene

Known as: E2-230K, UBE2O, ubiquitin conjugating enzyme E2 O 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
0246820132017

Papers overview

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2017
2017
UBE2O is localized in the 17q25 locus, which is known to be amplified in human cancers, but its role in tumorigenesis remains… (More)
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2017
2017
Many nascent proteins are assembled into multiprotein complexes of defined stoichiometry. Imbalances in the synthesis of… (More)
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2017
2017
BACKGROUND UBE2O is proposed as a ubiquitin-conjugating enzyme, but its function was largely unknown. METHODS Mass spectrometry… (More)
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2017
2017
Chromosomal translocations of the mixed-lineage leukemia (MLL) gene with various partner genes result in aggressive leukemia with… (More)
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2017
2017
  • Cancer discovery
  • 2017
Ube2o deletion suppresses the growth of breast and prostate cancers and extends survival in mice. 
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2017
2017
Ubiquitin-conjugating enzyme E2O (UBE2O) is upregulated in human cancers. We have demonstrated that genetic deletion or… (More)
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2017
2017
During terminal differentiation, the global protein complement is remodeled, as epitomized by erythrocytes, whose cytosol is ~98… (More)
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2014
2014
The tumor suppressor BAP1 interacts with chromatin-associated proteins and regulates cell proliferation, but its mechanism of… (More)
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2013
2013
Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is a key regulator of the activation of transcription factor NF… (More)
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2013
2013
SMAD6 is a crucial feedback inhibitory regulator of bone morphogenetic protein (BMP)/SMAD signalling. Although little is known… (More)
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