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U2AF

Known as: U2 accessory factor 
A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The U2AF heterodimer has been well studied for its role in defining functional 3′ splice sites in pre-mRNA splicing, but many… Expand
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Highly Cited
2012
Highly Cited
2012
One of the earliest steps in metazoan pre-mRNA splicing involves binding of U2 snRNP auxiliary factor (U2AF) 65 KDa subunit to… Expand
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Highly Cited
2011
Highly Cited
2011
Many cellular functions involve multi-domain proteins, which are composed of structurally independent modules connected by… Expand
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Highly Cited
2007
Highly Cited
2007
The U2AF-homology motif (UHM) mediates protein-protein interactions between factors involved in constitutive RNA splicing. Here… Expand
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Highly Cited
2006
Highly Cited
2006
Discrimination between splice sites and similar, nonsplice sequences is essential for correct intron removal and messenger RNA… Expand
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Highly Cited
2005
Highly Cited
2005
Fas exon 6 can be included or skipped to generate mRNAs encoding, respectively, a membrane bound form of the receptor that… Expand
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2002
2002
TAP/NXF1 is a conserved mRNA export receptor serving as a link between messenger ribonucleoproteins (mRNPs) and the nuclear pore… Expand
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Highly Cited
1999
Highly Cited
1999
In metazoans, spliceosome assembly is initiated through recognition of the 5′ splice site by U1 snRNP and the polypyrimidine… Expand
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1993
1993
Several fission yeast temperature-sensitive mutants defective in pre-mRNA processing (prp- mutants) at the nonpermissive… Expand
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Highly Cited
1988
Highly Cited
1988
Pre-mRNA splicing complex assembly is mediated by two specific pre-mRNA-snRNP interactions: U1 snRNP binds to the 5' splice site… Expand
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