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U 76074
Known as:
U-76,074
, U-76074
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Benzofurans
Indoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
A clinical pharmacokinetics study of carzelesin given by short-term intravenous infusion in a phase I study
O. van Tellingen
,
C. Punt
,
+7 authors
J. Beijnen
Cancer Chemotherapy and Pharmacology
1998
Corpus ID: 8714468
Abstract We investigated the pharmacokinetic behavior of carzelesin in 31 patients receiving this drug by 10-min intravenous…
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1996
1996
Phase I clinical and pharmacokinetic study of carzelesin (U-80244) given daily for five consecutive days.
I. Wolff
,
K. Bench
,
+7 authors
Cristiana Sessa
Clinical Cancer Research
1996
Corpus ID: 30122811
Carzelesin (U-80244), one of the synthetic DNA minor groove binding cyclopropylpyrroloindole analogues, was selected for clinical…
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1996
1996
Systematic study on the chemical stability of the prodrug antitumor agent carzelesin (U-80,244)
J. D. Vries
,
W. G. Doppenberg
,
R. Henrar
,
A. Bult
,
J. Beijnen
Journal of Pharmacy and Science
1996
Corpus ID: 6499953
The chemical stability of the novel anticancer agent carzelesin in aqueous buffer/acetonitrile (1:1, v/v) mixtures has been…
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1995
1995
The influence of formulation excipients on the stability of the novel antitumor agent carzelesin (U-80,244).
J. D. Jonkman-de Vries
,
H. Rosing
,
R. Henrar
,
A. Bult
,
J. Beijnen
PDA journal of pharmaceutical science and…
1995
Corpus ID: 8985047
The stability of carzelesin in a polyethylene glycol 400 (PEG 400)/absolute ethanol/polysorbate 80 (Tween 80) (6:3:1, v/v/v…
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1994
1994
Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma.
O. van Tellingen
,
Esther M. Pels
,
+4 authors
W. Nooijen
Journal of Chromatography A
1994
Corpus ID: 37572224
Highly Cited
1992
Highly Cited
1992
Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.
L. Li
,
T. Dekoning
,
+7 authors
M. Prairie
Cancer Research
1992
Corpus ID: 17469137
The cyclopropylpyrroloindole analogues are DNA minor-groove binders containing a cyclopropyl group, which mediates N3-adenine…
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