U 18666A

Known as: U 18,666A, U18666A, U-18666A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05101519762018

Papers overview

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Highly Cited
2007
Highly Cited
2007
Niemann-Pick C (NPC) disease is an autosomal recessive lipid storage disorder characterized by a disruption of sphingolipid and… (More)
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2007
2007
BACKGROUND Pathological accumulation of cholesterol in late endosomes is observed in lysosomal storage diseases such as Niemann… (More)
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Highly Cited
2004
Highly Cited
2004
We have previously established that the ABCA1 transporter, which plays a critical role in the lipidation of extracellular… (More)
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Highly Cited
2004
Highly Cited
2004
Niemann-Pick type C disease (NPC) is characterized by neurodegeneration secondary to impaired cholesterol trafficking and… (More)
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Highly Cited
2002
Highly Cited
2002
In advanced atherosclerosis, macrophage foam cells progressively accumulate large amounts of unesterified or "free" cholesterol… (More)
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Highly Cited
2001
Highly Cited
2001
People homozygous for mutations in the Niemann-Pick type C1 (NPC1) gene have physiological defects, including excess accumulation… (More)
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Highly Cited
2000
Highly Cited
2000
In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the… (More)
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Highly Cited
2000
Highly Cited
2000
Cholesterol accumulates to massive levels in cells from Niemann-Pick type C (NP-C) patients and in cells treated with class 2… (More)
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Highly Cited
1999
Highly Cited
1999
Niemann-Pick type C (NPC) disease is a severe cell lipidosis characterized by the accumulation of unesterified cholesterol in the… (More)
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Highly Cited
1995
Highly Cited
1995
Considerable evidence supports the involvement of acyl-CoA:cholesterol acyltransferase (ACAT) in the maintenance of intracellular… (More)
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