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U 18666A

Known as: U 18,666A, U18666A, U-18666A 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Niemann‐Pick C1 (NPC1) is a lysosomal membrane protein that exports cholesterol derived from receptor‐mediated uptake of LDL, and… 
Review
2009
Review
2009
The multiple actions of U18666A have enabled major discoveries in lipid research and contributed to understanding the… 
Highly Cited
2004
Highly Cited
2004
Glycosphingolipids are endocytosed and targeted to the Golgi apparatus but are mistargeted to lysosomes in sphingolipid storage… 
Highly Cited
2001
Highly Cited
2001
People homozygous for mutations in the Niemann-Pick type C1 (NPC1) gene have physiological defects, including excess accumulation… 
Highly Cited
2000
Highly Cited
2000
In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the… 
Highly Cited
1999
Highly Cited
1999
Niemann-Pick type C (NPC) disease is a severe cell lipidosis characterized by the accumulation of unesterified cholesterol in the… 
Highly Cited
1999
Highly Cited
1999
The abundance of cell cholesterol is governed by multiple regulatory proteins in the endoplasmic reticulum (ER) which, in turn… 
Highly Cited
1995
Highly Cited
1995
Considerable evidence supports the involvement of acyl-CoA:cholesterol acyltransferase (ACAT) in the maintenance of intracellular… 
Highly Cited
1992
Highly Cited
1992