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U 18666A

Known as: U 18,666A, U18666A, U-18666A 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
The multiple actions of U18666A have enabled major discoveries in lipid research and contributed to understanding the… Expand
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Highly Cited
2002
Highly Cited
2002
  • Bo Feng, I. Tabas
  • The Journal of Biological Chemistry
  • 2002
  • Corpus ID: 11351795
In advanced atherosclerosis, macrophage foam cells progressively accumulate large amounts of unesterified or “free” cholesterol… Expand
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Highly Cited
2001
Highly Cited
2001
People homozygous for mutations in the Niemann-Pick type C1 (NPC1) gene have physiological defects, including excess accumulation… Expand
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Highly Cited
2000
Highly Cited
2000
In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the… Expand
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Highly Cited
2000
Highly Cited
2000
Cholesterol accumulates to massive levels in cells from Niemann-Pick type C (NP-C) patients and in cells treated with class 2… Expand
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Highly Cited
1999
Highly Cited
1999
The abundance of cell cholesterol is governed by multiple regulatory proteins in the endoplasmic reticulum (ER) which, in turn… Expand
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Highly Cited
1999
Highly Cited
1999
Niemann-Pick type C (NPC) disease is a severe cell lipidosis characterized by the accumulation of unesterified cholesterol in the… Expand
Highly Cited
1995
Highly Cited
1995
Considerable evidence supports the involvement of acyl-CoA:cholesterol acyltransferase (ACAT) in the maintenance of intracellular… Expand
Highly Cited
1992
Highly Cited
1992
Fluorescent microscopic examination of fibroblasts cultured with low density lipoprotein (LDL) and progesterone (10 micrograms/ml… Expand
Highly Cited
1989
Highly Cited
1989
In mammalian cells, low density lipoprotein (LDL) is bound, internalized, and delivered to lysosomes where LDL-cholesteryl esters… Expand
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