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U 18666A

Known as: U 18,666A, U18666A, U-18666A 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells
2004
2004
Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells.
2004
2004
Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor Published, JLR Papers in Press, April 21, 2004. DOI 10.1194/jlr…
Induction of cataracts in experimental animals is a common toxic feature of oxidosqualene cyclase (OSC) inhibitors. U18666A has… 
1993
1993
Calcium activated proteolysis and protein modification in the U18666A cataract.
Proteolytic modifications of specific water soluble lens crystallins during U18666A cataract formation in young rats were… 
Highly Cited
1992
Highly Cited
1992
Progesterone blocks cholesterol translocation from lysosomes.
1991
1991
Characterization of Chinese hamster ovary cells that are resistant to 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one inhibition of low density lipoprotein-derived cholesterol metabolism.
Highly Cited
1986
Highly Cited
1986
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis by oxylanosterols.
Treatment of rat intestinal epithelial cell cultures with the oxidosqualene cyclase inhibitor, 3 beta-[2-(diethylamino)-ethoxy… 
1985
1985
Regional distribution of lipids and phospholipase A2 activity in normal and cataractous rat lens.
The objectives of this study were to investigate the cause of the great difference in the concentration of phospholipids between… 
Highly Cited
1984
Highly Cited
1984
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by oxysterol by-products of cholesterol biosynthesis. Possible mediators of low density lipoprotein action.
Highly Cited
1983
Highly Cited
1983
Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures.
The relationship between cholesterol and ubiquinone synthesis in rat intestinal epithelial cell cultures was examined by using 3… 
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