Tumor Model

Cells, tissues, or animals used to study the development and progression of cancer, and to test new treatments before they are given to humans… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
010020030019692017

Papers overview

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Highly Cited
2010
Highly Cited
2010
MicroRNAs (miRNAs) are increasingly implicated in the regulation of metastasis. Despite their potential as targets for anti… (More)
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Highly Cited
2010
Highly Cited
2010
Angiogenesis is a hallmark of malignant neoplasias, as the formation of new blood vessels is required for tumors to acquire… (More)
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Highly Cited
2008
Highly Cited
2008
Using a syngeneic p53-null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified, by… (More)
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Highly Cited
2006
Highly Cited
2006
New research findings have revealed a key role for vascular endothelial growth factor (VEGF) in the stimulation of angiogenesis… (More)
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Highly Cited
2005
Highly Cited
2005
We have previously described a panel of serially transplantable glioblastoma multiforme xenograft lines established by direct… (More)
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Highly Cited
2001
Highly Cited
2001
Metastasis to local lymph nodes via the lymphatic vessels is a common step in the spread of solid tumors. To investigate the… (More)
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Highly Cited
2001
Highly Cited
2001
The 4T1 mammary carcinoma is a transplantable tumor cell line that is highly tumorigenic and invasive and, unlike most tumor… (More)
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Highly Cited
2001
Highly Cited
2001
The rabbit VX2 tumor when implanted in the liver has proven convenient as a model for studying hepatocellular carcinomas. However… (More)
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Highly Cited
1999
Highly Cited
1999
Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder characterized by increased incidence of benign and malignant… (More)
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Highly Cited
1980
Highly Cited
1980
A new tumor model system (RIF-1) was developed that is very suitable for studies in which clonogenic survival is compared with… (More)
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