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Tuberculosis, Multidrug-Resistant

Known as: MDR-TB, multidrug resistant tuberculosis, Multidrug-Resistant TB 
Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance… Expand
National Institutes of Health

Related topics

Related topics

13 relations
Antitubercular AgentsDrug Resistance, BacterialDrug Resistance, MicrobialDrug Resistance, Multiple, Bacterial
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Broader (1)

Tuberculosis, Drug-Resistant

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis.
BACKGROUND The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and mortality worldwide. Due to… Expand
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Review
2017
Review
2017
Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors
Abstract Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye… Expand
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Review
2017
Review
2017
Treatment of isoniazid-resistant tuberculosis with first-line drugs: a systematic review and meta-analysis.
BACKGROUND The results of some reports have suggested that treatment of isoniazid-resistant tuberculosis with the recommended… Expand
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Review
2017
Review
2017
The respiratory threat posed by multidrug resistant Gram‐negative bacteria
Respiratory infections are a major cause of global mortality and morbidity. In recent years, an increased incidence of multidrug… Expand
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Review
2017
Review
2017
Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis
Only 25% of multidrug-resistant tuberculosis (MDR-TB) cases are currently diagnosed. Line probe assays (LPAs) enable rapid drug… Expand
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Review
2016
Review
2016
Mechanisms of Resistance to Aminoglycoside Antibiotics: Overview and Perspectives.
Aminoglycoside (AG) antibiotics are used to treat many Gram-negative and some Gram-positive infections and, importantly… Expand
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Review
2015
Review
2015
Use of standardised patients to assess quality of tuberculosis care: a pilot, cross-sectional study.
BACKGROUND Existing studies of the quality of tuberculosis care have relied on recall-based patient surveys, questionnaire… Expand
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Highly Cited
2011
Highly Cited
2011
Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study
BACKGROUND The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect tuberculosis and its multidrug-resistant form with… Expand
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Highly Cited
2009
Highly Cited
2009
The diarylquinoline TMC207 for multidrug-resistant tuberculosis.
BACKGROUND The diarylquinoline TMC207 offers a new mechanism of antituberculosis action by inhibiting mycobacterial ATP synthase… Expand
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Highly Cited
1993
Highly Cited
1993
Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis
Control of tuberculosis is threatened by widespread emergence of drug resistance in Mycobacterium tuberculosis. Understanding the… Expand
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