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Tryptic Digestion

Known as: Trypsin Digestion 
A technique for proteolysis of proteins into peptides at lysine or arginine by treatment with the pancreatic enzyme trypsin.
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
Selective analysis of phosphopeptides within a protein mixture by chemical modification, reversible biotinylation and mass spectrometry.
A new method combining chemical modification and affinity purification is described for the characterization of serine and… 
Highly Cited
1992
Highly Cited
1992
Influence of cysteine to cysteic acid oxidation on the collision-activated decomposition of protonated peptides: Evidence for intraionic interactions
Highly Cited
1991
Highly Cited
1991
Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes.
Highly Cited
1988
Highly Cited
1988
Characterization of the regulatory thioredoxin site of phosphoribulokinase.
Highly Cited
1986
Highly Cited
1986
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicry.
Human immunodeficiency virus (HIV), the retrovirus that causes the acquired immunodeficiency syndrome, is cytopathic for CD4+ T… 
Highly Cited
1986
Highly Cited
1986
Profile of the disulfide bonds in acetylcholinesterase.
Highly Cited
1982
Highly Cited
1982
Lipid effects on the binding properties of a reconstituted insulin receptor.
Highly Cited
1978
Highly Cited
1978
The amino acid sequence of rabbit skeletal alpha-tropomyosin. The NH2-terminal half and complete sequence.
Highly Cited
1975
Highly Cited
1975
Characteristics of a solubilized thyrotropin receptor from bovine thyroid plasma membranes.
Highly Cited
1972
Highly Cited
1972
Chemical characterization and surface orientation of the major glycoprotein of the human erythrocyte membrane.
The major glycoprotein of the human erythrocyte membrane has been isolated by treatment with lithium di-iodosalicylate and found… 
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