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Trough Concentration

Known as: Conc Trough, Ctrough 
Concentration at end of dosing interval.
National Institutes of Health

Related topics

Related topics

2 relations
CDISC SDTM Pharmacokinetic Parameter Long Name TerminologyClinical Data Interchange Standards Consortium Terminology

Papers overview

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2019
2019
A 52-Week Study of Dose Adjusted Subcutaneous Testosterone Enanthate in Oil Self-Administered via Disposable Auto-Injector
2016
2016
Dolutegravir as maintenance monotherapy: first experiences in HIV-1 patients.
BACKGROUND Dolutegravir is recommended as part of combination ART (cART) for HIV-1-infected patients. Toxicities, drug… 
2009
2009
Pharmacokinetics and Safety of Etravirine Administered Once or Twice Daily After 2 Weeks Treatment With Efavirenz in Healthy Volunteers
Objective:To assess the pharmacokinetics of etravirine once and twice daily without and with a preceding efavirenz intake period… 
Highly Cited
2009
Highly Cited
2009
Protease Inhibitor Resistance Analysis in the MONARK Trial Comparing First-Line Lopinavir-Ritonavir Monotherapy to Lopinavir-Ritonavir plus Zidovudine and Lamivudine Triple Therapy
ABSTRACT The MONARK study was a pilot randomized trial comparing the safety and efficacy of lopinavir-ritonavir (LPV/r… 
Review
2005
Review
2005
Wasting your organ with your lifestyle and receiving a new one?
Alcoholic liver disease is the leading cause of end-stage liver disease and the second most common indication for liver… 
2004
2004
Pharmacokinetics of Enfuvirtide in Pediatric Human Immunodeficiency Virus 1-Infected Patients Receiving Combination Therapy
Background: Enfuvirtide is the first of a new class of antiretroviral agents, the fusion inhibitors. Objectives: The primary… 
Highly Cited
2003
Highly Cited
2003
Safety and Trough Concentrations of Nevirapine Prophylaxis Given Daily, Twice Weekly, or Weekly in Breast-Feeding Infants From Birth to 6 Months
Despite the success of antiretroviral prophylaxis in reducing mother-to-child HIV-1 transmission, postpartum transmission through… 
2003
2003
Individualizing salvage regimens: the inhibitory quotient (Ctrough/IC50) as predictor of virological response.
Increased drug levels could overcome resistance and improve the response to a salvage regimen. We evaluate the inhibitory… 
2003
2003
Considerations in Analyzing Single‐Trough Concentrations Using Mixed‐Effects Modeling
The purpose of this study was to assess the effect of trial design and data analysis choices on the bias and precision of… 
1997
1997
Tolerability and Pharmacokinetics of Monotherapy Felbamate Doses of 1,200–6,000 mg/day in Subjects with Epilepsy
: Purpose: Felbamate (FBM) pharmacokinetic parameters, safety and tolerability in the dose range of 1,200–6,000 mg/day were… 
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