Trough Concentration

Known as: Conc Trough, Ctrough 
Concentration at end of dosing interval.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
BACKGROUND & AIMS Infliximab, a tumor necrosis factor antagonist, is effective for treating patients with Crohn's disease (CD… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
2014
2014
The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2013
2013
OBJECTIVE Tenofovir disoproxil fumarate (TDF) is known to induce renal dysfunction in HIV-infected patients. The aim of this… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Several single-center studies have suggested that higher doses of vancomycin, aimed at producing trough concentrations of >15 mg… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Voriconazole is approved for treating invasive fungal infections. We examined voriconazole exposure-response relationships for… (More)
  • table 1
  • table 3
  • table 2
  • table 4
  • figure 1
Is this relevant?
2011
2011
BACKGROUNDS Variability of blood trough concentration (C0) in immunosuppressant leads to rejection and graft loss after kidney… (More)
Is this relevant?
2011
2011
STUDY OBJECTIVE To assess and validate the effectiveness of a newly constructed vancomycin dosing nomogram in achieving target… (More)
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Imatinib mesylate (IM) trough concentration varies among IM-treated chronic myeloid leukemia (CML) patients. Although IM… (More)
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
2007
2007
BACKGROUND Adequate antiretroviral exposure during pregnancy is critical to prevent the vertical transmission of HIV and for… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
AIM This study investigated the effects of St John's wort extract (SJW) on the pharmacokinetics and metabolism of the… (More)
Is this relevant?