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Troponin T, Cardiac Muscle

Known as: cTnT, TnTc, Cardiac Muscle Troponin T 
Troponin T, cardiac muscle (298 aa, ~36 kDa) is encoded by the human TNNT2 gene. This protein plays a role in cardiac muscle contraction.
National Institutes of Health

Related topics

Related topics

17 relations
Cardiac Muscle ContractionCell MovementCytokinesisCytoplasmic matrix

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling
Objective: To report the frequency of single and multiple gene mutations in an Australian cohort of patients with hypertrophic… 
Highly Cited
2002
Highly Cited
2002
Predictive Value of Cardiac Troponin I and T for Subsequent Death in End-Stage Renal Disease
Background—This study determined the prevalence of increased cardiac troponin I (cTnI) and T (cTnT) in end-stage renal disease… 
Highly Cited
2002
Highly Cited
2002
Functional consequences of caspase activation in cardiac myocytes
Cardiomyocyte apoptosis is present in many cardiac disease states, including heart failure and ischemic heart disease. Apoptosis… 
Highly Cited
2000
Highly Cited
2000
Independent prognostic value of cardiac troponin T in patients with confirmed pulmonary embolism.
BACKGROUND Cardiac troponin T (cTnT) is a sensitive and specific marker, allowing the detection of even minor myocardial cell… 
Highly Cited
2000
Highly Cited
2000
Cardiac troponins I and T are biological markers of left ventricular dysfunction in septic shock.
BACKGROUND Cardiac depression in severe sepsis and septic shock is characterized by left ventricular (LV) failure. To date, it is… 
Highly Cited
1999
Highly Cited
1999
RNA expression of cardiac troponin T isoforms in diseased human skeletal muscle.
BACKGROUND The expression of multiple cardiac troponin T (cTnT) isoforms has been demonstrated in diseased human skeletal muscle… 
Highly Cited
1998
Highly Cited
1998
Cardiac troponin T isoforms expressed in renal diseased skeletal muscle will not cause false-positive results by the second generation cardiac troponin T assay by Boehringer Mannheim.
The purpose of this study was to determine whether the two monoclonal anti-cardiac troponin T (cTnT) antibodies (MAbs) used in… 
Highly Cited
1997
Highly Cited
1997
Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease: evidence of cardiac troponin T expression in skeletal muscle.
Serum cardiac troponin T (cTnT) concentrations are frequently increased in chronic dialysis patients as measured by the first… 
Highly Cited
1997
Highly Cited
1997
Predictive value of cardiac troponin T in pediatric patients at risk for myocardial injury.
BACKGROUND Biochemical markers have not been routinely used in children at risk for myocardial damage. Yet, because of somatic… 
Highly Cited
1992
Highly Cited
1992
The prognostic value of serum troponin T in unstable angina.
BACKGROUND Cardiac troponin T is a regulatory contractile protein not normally found in blood. Its detection in the circulation… 
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