Trisomy 12

A chromosomal abnormality consisting of the presence of a third copy of chromosome 12 in somatic cells.
National Institutes of Health

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Topic mentions per year

1974-2018
0102019742018

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Highly Cited
2013
Highly Cited
2013
Clonal evolution is a key feature of cancer progression and relapse. We studied intratumoral heterogeneity in 149 chronic… (More)
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Highly Cited
2012
Highly Cited
2012
Two recent studies reported whole-genome sequencing of chronic lymphocytic leukemia (CLL) samples and found repeated mutations in… (More)
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Highly Cited
2012
Highly Cited
2012
Trisomy 12, the third most frequent chromosomal aberration in chronic lymphocytic leukemia (CLL), confers an intermediate… (More)
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Highly Cited
2002
Highly Cited
2002
This study evaluates the prognostic significance of genetic abnormalities (detected at or shortly after presentation), clinical… (More)
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Highly Cited
1999
Highly Cited
1999
Despite having several characteristics of naïve B cells, chronic lymphocytic leukemia (CLL) cells have been shown in some cases… (More)
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Highly Cited
1999
Highly Cited
1999
Despite having several characteristics of naı̈ve B cells, chronic lymphocytic leukemia (CLL) cells have been shown in some cases… (More)
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Highly Cited
1996
Highly Cited
1996
We have analysed the clinical and laboratory features in 544 patients with chronic lymphocytic leukaemia (CLL) with available… (More)
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1994
1994
The incidence of trisomy 12 was studied by conventional chromosome analysis in 111 patients referred as B-cell chronic… (More)
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1991
1991
Interphase cytogenetics by means of in situ hybridization with the chromosome 12-specific biotinylated alpha satellite DNA probe… (More)
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Highly Cited
1990
Highly Cited
1990
BACKGROUND AND METHODS Specific chromosomal abnormalities have been shown to affect the overall survival of patients with acute… (More)
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