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Trisomy 12

A chromosomal abnormality consisting of the presence of a third copy of chromosome 12 in somatic cells.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Clonal evolution is a key feature of cancer progression and relapse. We studied intratumoral heterogeneity in 149 chronic… Expand
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Highly Cited
2012
Highly Cited
2012
Two recent studies reported whole-genome sequencing of chronic lymphocytic leukemia (CLL) samples and found repeated mutations in… Expand
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Highly Cited
2012
Highly Cited
2012
PURPOSE We investigated the safety and efficacy of bendamustine and rituximab (BR) in previously untreated patients with chronic… Expand
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Highly Cited
2012
Highly Cited
2012
Trisomy 12, the third most frequent chromosomal aberration in chronic lymphocytic leukemia (CLL), confers an intermediate… Expand
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Highly Cited
2011
Highly Cited
2011
PURPOSE The objective of this trial was to evaluate safety and efficacy of bendamustine combined with rituximab (BR) in patients… Expand
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Highly Cited
2002
Highly Cited
2002
This study evaluates the prognostic significance of genetic abnormalities (detected at or shortly after presentation), clinical… Expand
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Highly Cited
1999
Highly Cited
1999
Despite having several characteristics of naïve B cells, chronic lymphocytic leukemia (CLL) cells have been shown in some cases… Expand
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Highly Cited
1997
Highly Cited
1997
Deletions of the long arm of chromosome 11 (11q) are one of the most frequent structural chromosome aberrations in various types… Expand
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Highly Cited
1996
Highly Cited
1996
We have analysed the clinical and laboratory features in 544 patients with chronic lymphocytic leukaemia (CLL) with available… Expand
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Highly Cited
1990
Highly Cited
1990
BACKGROUND AND METHODS Specific chromosomal abnormalities have been shown to affect the overall survival of patients with acute… Expand
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