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Trisomy 12

A chromosomal abnormality consisting of the presence of a third copy of chromosome 12 in somatic cells.
National Institutes of Health

Related topics

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42 relations
Aleukemic Chronic Lymphocytic LeukemiaBenign Ovarian Luteinized ThecomaBenign Ovarian ThecomaBlastoid Variant Mantle Cell Lymphoma

Papers overview

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2013
2013
Genomic variation by whole-genome SNP mapping arrays predicts time-to-event outcome in patients with chronic lymphocytic leukemia: a comparison of CLL and HapMap genotypes.
Highly Cited
2012
Highly Cited
2012
Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults in Western countries. Chromosomal abnormalities… 
1997
1997
Detection of trisomy 12 and Rb-deletion in CD34+ cells of patients with B-cell chronic lymphocytic leukemia.
B-cell chronic lymphocytic leukemia (B-CLL) is a slowly progressive disease characterized by the clonal expansion of CD5+/CD23+ B… 
1995
1995
Trisomy 12 in Richter's transformation of chronic lymphocytic leukemia.
Conventional cytogenetic data and fluorescence in situ hybridization (FISH) interphase cytogenetic studies have shown that… 
Review
1994
Review
1994
Cytogenetic and molecular abnormalities in chronic lymphocytic leukaemia.
Highly Cited
1993
Highly Cited
1993
Trisomy 12 in chronic lymphoid leukemias--a metaphase and interphase cytogenetic analysis.
Trisomy 12 has been shown to be one of the most common chromosome abnormalities in chronic lymphoid leukemias of B-cell origin… 
Review
1992
Review
1992
Primary, single, autosomal trisomies associated with haematological disorders. United Kingdom Cancer Cytogenetics Group (UKCCG).
Highly Cited
1992
Highly Cited
1992
Mosaicism of trisomy 12 in chronic lymphocytic leukemia detected by non-radioactive in situ hybridization.
Cytogenetic analysis using banding techniques of B-chronic lymphocytic leukemia (CLL) is hampered by the difficult in vitro… 
Highly Cited
1983
Highly Cited
1983
Clonal chromosome abnormalities in patients with Waldenström's and CLL-associated macroglobulinemia: significance of trisomy 12.
We performed cytogenetic analyses by Q- and G-banding techniques of unstimulated or B-mitogen-stimulated spleen, bone marrow, and… 
1983
1983
Chromosome abnormalities in chronic lymphocytic leukemia revealed by TPA as a mitogen.
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