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Triptolide Analog

A water soluble analog of the diterpenoid triepoxide triptolide isolated from the Chinese herb Tripterygium wilfordii Hook.f., with potential… Expand
National Institutes of Health

Papers overview

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2019
2019
The aim of this paper was to compare the performance of acute liver injury in mice induced by Tripterygium Glycosides Tablets… Expand
2018
2018
Background: Tripterygium wilfordii (TW) is widely employed to treat rheumatoid arthritis and autoimmune disorders clinically… Expand
2017
2017
Triptolide (TP) is the major active component of Tripterygium wilfordii Hook F (TWHF) and possesses multiple pharmacological… Expand
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2014
2014
AbstractPurpose Triptolide induces cancer cell apoptosis by inhibiting RNA synthesis and signaling pathways like NF-κB. We… Expand
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2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Cisplatin is an anticancer drug used in treatment for many… Expand
2012
2012
Objective To investigate Gender-related differences in the pharmacokinetics of MC002,a novel prodrug of triptolide.Methods MC002… Expand
Review
2012
Review
2012
The Chinese traditional herb Tripterygium wilfordii Hook f (TwHF) has been widely used in the treatment of autoimmune and… Expand
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2011
2011
The composite tissue allotransplantations (CTA) are not routinely performed for tissue reconstruction due to the potentially… Expand
2009
2009
The pathogenesis of hypereosinophilic syndrome (HES) in some patients is highly dependent on FIP1‐Like‐1 (FIP1L1)–platelet… Expand
Highly Cited
2005
Highly Cited
2005
A series of triptolide analogs have been successfully synthesized. In the present study we demonstrated one of them, (5R)-5… Expand