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Triptolide Analog

A water soluble analog of the diterpenoid triepoxide triptolide isolated from the Chinese herb Tripterygium wilfordii Hook.f., with potential… 
National Institutes of Health

Papers overview

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2019
2019
[Effects of Tripterygium Glycosides Tablets from 6 different manufacturers on acute liver injury of normal mice].
The aim of this paper was to compare the performance of acute liver injury in mice induced by Tripterygium Glycosides Tablets… 
2017
2017
(5R)-5-hydroxytriptolide ameliorates anti-glomerular basement membrane glomerulonephritis in NZW mice by regulating Fcγ receptor signaling
(5R)-5-hydroxytriptolide (LLDT-8) is a novel triptolide analog that has been identified as a promising candidate for treating… 
2014
2014
Abstract 5110: The role triptolide in sensitizing lung tumor cells to cisplatin-induced apoptosis
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Cisplatin is an anticancer drug used in treatment for many… 
2012
2012
Gender-related Differences in Pharmacokinetics of Novel Prodrug of Triptolide MC002 in Rats
Objective To investigate Gender-related differences in the pharmacokinetics of MC002,a novel prodrug of triptolide.Methods MC002… 
2011
2011
CANADIAN SOCIETY OF TRANSPLANTATION SOCIÉTÉ CANADIENNE DE TRANSPLANTATION ANNUAL SCIENTIFIC MEETING RÉUNION SCIENTIFIQUE ANNUELLE
The composite tissue allotransplantations (CTA) are not routinely performed for tissue reconstruction due to the potentially… 
2009
2009
Triptolide abrogates oncogene FIP1L1‐PDGFRα addiction and induces apoptosis in hypereosinophilic syndrome
The pathogenesis of hypereosinophilic syndrome (HES) in some patients is highly dependent on FIP1‐Like‐1 (FIP1L1)–platelet… 
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