Transgenic Model

A disease in a transgenic animal with pathologic mechanisms sufficiently similar to those of a human disease for the animal disease to serve as a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
012319932017

Papers overview

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Highly Cited
2006
Highly Cited
2006
Considerable animal and human data have indicated that selenium is effective in reducing the incidence of several different types… (More)
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Highly Cited
2005
Highly Cited
2005
The cytochrome P450 (P450) CYP2E1 enzyme metabolizes and activates a wide array of toxicological substrates, including alcohols… (More)
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Highly Cited
2004
Highly Cited
2004
OVE26 mice are a transgenic model of severe early-onset type 1 diabetes. These mice develop diabetes within the first weeks of… (More)
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2002
2002
We show here using a transgenic model that human C-reactive protein (CRP) protects against experimental allergic… (More)
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Highly Cited
2002
Highly Cited
2002
Many diabetic patients suffer from cardiomyopathy, even in the absence of vascular disease. This diabetic cardiomyopathy… (More)
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2001
2001
We previously reported a novel transgenic model expressing human angiotensinogen from the kidney androgen-regulated protein… (More)
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1998
1998
In previous studies we have demonstrated that transforming growth factor (TGF)-alpha/c-myc double transgenic mice exhibit an… (More)
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1997
1997
Infection of the human cervix with certain papillomavirus subtypes is associated with the development of neoplastic squamous… (More)
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Highly Cited
1996
Highly Cited
1996
We have generated a transgenic model consisting of both the human renin and human angiotensinogen genes to study further the role… (More)
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1994
1994
Transgenic mice with tissue-specific expression of the human insulin gene in the beta cells of the pancreas do not produce… (More)
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