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Transcript
Known as:
Transcripts
The initial RNA molecule produced by transcription.
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Transcript-level expression analysis of RNA-seq experiments with HISAT, StringTie and Ballgown
M. Perțea
,
Daehwan Kim
,
G. Pertea
,
J. Leek
,
S. Salzberg
Nature Protocols
2016
Corpus ID: 3338114
High-throughput sequencing of mRNA (RNA-seq) has become the standard method for measuring and comparing the levels of gene…
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Highly Cited
2013
Highly Cited
2013
De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis
B. Haas
,
A. Papanicolaou
,
+20 authors
A. Regev
Nature Protocols
2013
Corpus ID: 14551253
De novo assembly of RNA-seq data enables researchers to study transcriptomes without the need for a genome sequence; this…
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Highly Cited
2012
Highly Cited
2012
Differential analysis of gene regulation at transcript resolution with RNA-seq
C. Trapnell
,
David G Hendrickson
,
Martin Sauvageau
,
L. Goff
,
J. Rinn
,
L. Pachter
Nature Biotechnology
2012
Corpus ID: 9253369
Differential analysis of gene and transcript expression using high-throughput RNA sequencing (RNA-seq) is complicated by several…
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Highly Cited
2011
Highly Cited
2011
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li
,
Colin N. Dewey
BMC Bioinformatics
2011
Corpus ID: 13123189
BackgroundRNA-Seq is revolutionizing the way transcript abundances are measured. A key challenge in transcript quantification…
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Highly Cited
2010
Highly Cited
2010
Transcript assembly and abundance estimation from RNA-Seq reveals thousands of new transcripts and switching among isoforms
C. Trapnell
,
B. Williams
,
+6 authors
L. Pachter
Nature Biotechnology
2010
Corpus ID: 27061085
High-throughput mRNA sequencing (RNA-Seq) promises simultaneous transcript discovery and abundance estimation. However, this…
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Highly Cited
2001
Highly Cited
2001
A new mathematical model for relative quantification in real-time RT-PCR.
M. Pfaffl
Nucleic Acids Research
2001
Corpus ID: 9003591
Use of the real-time polymerase chain reaction (PCR) to amplify cDNA products reverse transcribed from mRNA is on the way to…
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Highly Cited
1998
Highly Cited
1998
Cluster analysis and display of genome-wide expression patterns.
M. Eisen
,
P. Spellman
,
P. Brown
,
D. Botstein
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 3010146
A system of cluster analysis for genome-wide expression data from DNA microarray hybridization is described that uses standard…
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Highly Cited
1998
Highly Cited
1998
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
A. Fire
,
Siqun Xu
,
M. Montgomery
,
S. A. Kostas
,
Samuel E. Driver
,
C. Mello
Nature
1998
Corpus ID: 4355692
Experimental introduction of RNA into cells can be used in certain biological systems to interfere with the function of an…
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Highly Cited
1993
Highly Cited
1993
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Rosalind C. Lee
,
Rhonda L. Feinbaum
,
V. Ambros
Cell
1993
Corpus ID: 205020975
Highly Cited
1983
Highly Cited
1983
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.
J. Dignam
,
R. Lebovitz
,
R. Roeder
Nucleic Acids Research
1983
Corpus ID: 1162926
We have developed a procedure for preparing extracts from nuclei of human tissue culture cells that directs accurate…
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