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Tranexamic Acid

Known as: trans-4-(Aminomethyl)cyclohexanecarboxylic Acid, Tranexamic Acid [Chemical/Ingredient], Acidum tranexamicum 
A synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the five lysine-binding sites of plasminogen… 
National Institutes of Health

Related topics

Related topics

29 relations
10 ML Tranexamic Acid 100 MG/ML Injection [Cyklokapron]Blood Coagulation DisordersBlood Coagulation FactorDecreased Fibrinolysis [PE]

Narrower (11)

AmchafibrinAnvitoffCyklokapronExacyl

Broader (1)

Antifibrinolytic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety
Objective To determine the effectiveness and safety of perioperative tranexamic acid use in patients undergoing total hip or knee… 
Review
2014
Review
2014
A systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement.
Intravenous tranexamic acid (TXA) has been shown to be effective in reducing blood loss and the need for transfusion after joint… 
Highly Cited
2013
Highly Cited
2013
The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty
PurposeReduction in blood loss during surgery stabilizes hemodynamic status and aids in recovery after total knee arthroplasty… 
Review
2011
Review
2011
Tranexamic acid in total knee replacement: a systematic review and meta-analysis.
We conducted a systematic review and meta-analysis of randomised controlled trials evaluating the effect of tranexamic acid (TXA… 
Highly Cited
2010
Highly Cited
2010
Tranexamic acid in hip fracture surgery: a randomized controlled trial.
BACKGROUND Hip fracture surgery may be associated with substantial blood loss. This study was designed to assess the efficacy and… 
Highly Cited
2007
Highly Cited
2007
New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
Background and aims: Several antibodies have been associated with Crohn’s disease and are associated with distinct clinical… 
Highly Cited
2006
Highly Cited
2006
Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial.
BACKGROUND Risks and costs of allogeneic blood transfusions mandate strategies to reduce blood loss in surgery. The objective of… 
Highly Cited
2001
Highly Cited
2001
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee.
We studied 99 patients who were undergoing total knee arthroplasty (TKA) to determine the optimum protocol for the administration… 
Highly Cited
1990
Highly Cited
1990
Multiple fluorescence in situ hybridization.
A method for multiple fluorescence in situ hybridization is described allowing the simultaneous detection of more than three… 
Review
1987
Review
1987
Clinical pharmacology of tranexamic acid.
Tranexamic acid (AMCA) is a potent antifibrinolytic drug occurring in two isomeric forms; the antifibrinolytic potency resides in… 
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