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Toponome

The toponome is the spatial network code of proteins and other biomolecules in morphologically intact cells and tissues. It is mapped and decoded by… 
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Papers overview

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2014
2014
Biological multi-channel microscopy data are often characterized by a high local entropy and phenotypically identical structures… 
2014
2014
The recent development of multivariate imaging techniques, such as the Toponome Imaging System (TIS), has facilitated the… 
2012
2012
The toponome of a cell describes the location and topological distribution of proteins across the cell. In toponomics, the… 
2012
2012
In this proof of principle study, automated fluorescence Toponome Imaging System (TIS) was applied to find protein network… 
2012
2012
Multi-tag bioimaging systems such as the toponome imaging system (TIS) require sophisticated analytical methods to extract… 
2011
2011
Bioimage computing is rapidly emerging as an important area in image based systems biology with an emphasis on spatiotemporal… 
2011
2011
Introduction In a proof of principle study, we have applied an automated fluorescence toponome imaging system (TIS) in order to… 
2011
2011
Identification, analysis and visualization of functional molecular networks are key objectives in systems biology and the logical… 
2007
2007
The Toponome Imaging System (TIS) is the latest development in automated multidimensional fluorescence microscopy. It is capable… 
2007
2007
A new challenge to data visualization has arisen from a new laboratory technique that is capable of imaging a large number of…