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Tolperisone

Known as: 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, Tolperisone [Chemical/Ingredient] 
A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Tolperisone, a piperidine derivative, is assigned to the group of centrally acting muscle relaxants and has been in clinical use… Expand
2006
2006
A simple high performance liquid chromatographic (HPLC) method was developed for the determination of tolperisone in human plasma… Expand
2006
2006
The specific, acute interaction of tolperisone, an agent used as a muscle relaxant and for the treatment of chronic pain… Expand
2005
2005
The spinal reflex depressant mechanism of tolperisone and some of its structural analogs with central muscle relaxant action was… Expand
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2005
2005
To study the efficacy and safety of tolperisone – a centrally acting muscle relaxant with membrane stabilizing activity – in the… Expand
2003
2003
The in vitro metabolism of tolperisone, 1-(4-methyl-phenyl)-2-methyl-3-(1-piperidino)-1-propanone-hydrochloride, a centrally… Expand
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2001
2001
The actions of tolperisone on single intact Ranvier nodes of the toad Xenopus were investigated by means of the Hodgkin-Huxley… Expand
1996
1996
  • G. Fels
  • Archiv der Pharmazie
  • 1996
  • Corpus ID: 38161223
Tolperisone (1), a muscle relaxant with lidocaine‐like activity, was compared to lidocaine (2) by molecular modeling methods… Expand
1992
1992
A stereoselective assay for the determination of tolperisone enantiomers in plasma by high performance liquid chromatography was… Expand
Highly Cited
1982
Highly Cited
1982
Effects of afloqualone on mono- (MSR) and poly-synaptic reflex (PSR) potentials and alpha- and gamma-rigidities were studied in… Expand