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Tolperisone

Known as: 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, Tolperisone [Chemical/Ingredient] 
A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodTolperisone Hydrochlorideagonistsanalogs & derivatives

Broader (1)

Muscle Relaxants, Central

Narrower (2)

MydetonMydocalm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Tolperisone: A Typical Representative of a Class of Centrally Acting Muscle Relaxants with Less Sedative Side Effects
Tolperisone, a piperidine derivative, is assigned to the group of centrally acting muscle relaxants and has been in clinical use… 
2006
2006
HPLC Determination of tolperisone in human plasma
A simple high performance liquid chromatographic (HPLC) method was developed for the determination of tolperisone in human plasma… 
2005
2005
Tolperisone-Type Drugs Inhibit Spinal Reflexes via Blockade of Voltage-Gated Sodium and Calcium Channels
The spinal reflex depressant mechanism of tolperisone and some of its structural analogs with central muscle relaxant action was… 
2005
2005
A randomized, double‐blind, placebo‐controlled study of the efficacy and safety of tolperisone in spasticity following cerebral stroke
To study the efficacy and safety of tolperisone – a centrally acting muscle relaxant with membrane stabilizing activity – in the… 
2005
2005
Simple pharmacological test battery to assess efficacy and side effect profile of centrally acting muscle relaxant drugs.
2003
2003
Identification of metabolic pathways involved in the biotransformation of tolperisone by human microsomal enzymes.
The in vitro metabolism of tolperisone, 1-(4-methyl-phenyl)-2-methyl-3-(1-piperidino)-1-propanone-hydrochloride, a centrally… 
1997
1997
Use of identical assay conditions for cocaine analog binding and dopamine uptake to identify potential cocaine antagonists.
1992
1992
Determination of tolperisone enantiomers in plasma and their disposition in rats.
A stereoselective assay for the determination of tolperisone enantiomers in plasma by high performance liquid chromatography was… 
1989
1989
Effects of some centrally acting muscle relaxants on spinal root potentials: A comparative study
1989
1989
Suppression of calcium current in a snail neurone by eperisone and its analogues.
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