Tolperisone

Known as: 1-Propanone, 2-methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-, Tolperisone [Chemical/Ingredient] 
A centrally acting muscle relaxant that has been used for the symptomatic treatment of spasticity and muscle spasm. (From Martindale, The Extra… (More)

Topic mentions per year

Topic mentions per year

1976-2017
0246819762017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
OBJECTIVE The aim of this study was to determine the pharmacokinetic profiles of oral tolperisone hydrochloride in healthy… (More)
Is this relevant?
2006
2006
A simple high performance liquid chromatographic (HPLC) method was developed for the determination of tolperisone in human plasma… (More)
Is this relevant?
2006
2006
The specific, acute interaction of tolperisone, an agent used as a muscle relaxant and for the treatment of chronic pain… (More)
Is this relevant?
2005
2005
The spinal reflex depressant mechanism of tolperisone and some of its structural analogs with central muscle relaxant action was… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2003
2003
Four patients with anaphylaxis attributed to the intake of the centrally acting muscle relaxant tolperisone hydrochloride… (More)
Is this relevant?
2003
2003
The in vitro metabolism of tolperisone, 1-(4-methyl-phenyl)-2-methyl-3-(1-piperidino)-1-propanone-hydrochloride, a centrally… (More)
  • table 2
  • table 1
  • figure 1
  • table 3
  • figure 2
Is this relevant?
2001
2001
A reversed phase high performance liquid chromatographic (RP-HPLC) method for the simultaneous determination of tolperisone (TP… (More)
Is this relevant?
2000
2000
The stereochemistry of tolperisone, a chiral aryl-alkyl basic ketone was investigated by means of circular dichroism (CD) and… (More)
Is this relevant?
1996
1996
Tolperisone (1), a muscle relaxant with lidocaine-like activity, was compared to lidocaine (2) by molecular modeling methods… (More)
Is this relevant?
1996
1996
The efficacy and safety of oral tolperisone hydrochloride (Mydocalm) in the treatment of painful reflex muscle spasm was assessed… (More)
Is this relevant?