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Todralazine

Known as: Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride, Todrazoline, Todralazine [Chemical/Ingredient] 
An antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.
National Institutes of Health

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9 relations

Broader (1)

Antihypertensive Agents

Narrower (1)

Binazine
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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2000
2000
Evaluation of the immunomodulatory activity of four compounds exerting antimutagenic effects on human lymphocytes in vitro
Four compounds previously described as antimutagenic for human lymphocytes in vitro were tested on their immunomodulatory… 
1995
1995
Evaluation of the mechanisms of todralazine effect on mutagenicity of benzo(a)pyrene.
We have previously described that todralazine markedly decreased mutagenicity of several indirect- and direct-acting mutagens. In… 
1994
1994
Study of the mechanism of todralazine antimutagenic activity: the effect upon mutagenicity of daunorubicine.
Todralazine markedly reduced the mutagenic activity of the standard direct-acting mutagen--daunorobicine (DRC)--in the Ames test… 
1982
1982
Effects of ecarazine, prazosin, phentolamine and hexamethonium on the vasopressor reflexes induced by bilateral carotid artery occlusion and head-up tilting in cats.
In order to examine clinical potential for ecarazine, prazosin, phentolamine and hexamethonium to cause orthostatic hypotension… 
1980
1980
Effect of 3-hydrazino-6[N, N-bis (2-hydroxyethyl) amino]-pyridazine (L 6150) on renin in hypertensive rats.
L 6150 is an antihypertensive drug classified as a vasodilator. We have reported its antihypertensive effect observed in three… 
1979
1979
[Inhibition of cyclic AMP phosphodiesterase activity by ecarazine hydrochloride, hydralazine and their metabolites (author's transl)].
1979
1979
Ecarazine Hydrochloride, Hydralazineおよび代謝物のPhosphodiesterase阻害活性について
1978
1978
Antihypertensive and antidiuretic effects of 3-hydrazino-6-[N, N-bis (2-hydroxyethyl) amino]-pyridazine (L 6150) in rats.
3-Hydrazino-6-[N,N-bis (2-hydroxyethyl)amino]-pyridazine (L 6150) has been reported as an antihypertensive vasodilator drug. We… 
1978
1978
Studies on ecarazine hydrochloride (apiracohl). II. Spectrofluorometric determination of ecarazine hydrochloride and its metabolite in plasma.
Spectrofluorometric assay for the quantitative determination of ecarazine hydrochloride (I) and its metabolite, 3-methyl-s… 
1976
1976
[Antihypertensive effects of ecarazine hydrochloride in essential hypertension and its action on the renin-aldosterone system].
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