Todralazine

Known as: Hydrazinecarboxylic acid, 2-(1-phthalazinyl)-, ethyl ester, monohydrochloride, Todrazoline, Todralazine [Chemical/Ingredient] 
An antihypertensive agent with both central and peripheral action; it has some central nervous system depressant effects.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2015
01219762015

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2015
2015
The Johns Hopkins Clinical Compound Library (JHCCL), a collection of Food and Drug Administration (FDA)-approved small molecules… (More)
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2007
2007
BACKGROUND/AIMS The aim of this study was to investigate the precise mechanism of liver failure by hydralazine derivatives, with… (More)
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2001
2001
The sensitivity of the available methods of apoptosis detection in lymphocyte cultures was tested. Cells were preincubated with… (More)
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2000
2000
Todralazine, an antihypertensive drug from the hydrazinophthalazine group, significantly decreased the activities of benzo[a… (More)
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1997
1997
Todralazine, an antihypertensive drug of the hydrazinoph-thalazine group, markedly decreased the mutagenic activity of potassium… (More)
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1996
1996
We studied the effects of long-term antihypertensive treatment on endothelial function in renal resistance arteries from… (More)
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1994
1994
Differential pulse polarography (DPP) is proposed as a direct method for the quantitation of todralazine and acetazolamide in… (More)
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1994
1994
Todralazine decreased the mutagenic activity of tested direct- and indirect-acting mutagens. Despite the marked differences… (More)
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1982
1982
In order to examine clinical potential for ecarazine, prazosin, phentolamine and hexamethonium to cause orthostatic hypotension… (More)
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1978
1978
3-Hydrazino-6-[N,N-bis (2-hydroxyethyl)amino]-pyridazine (L 6150) has been reported as an antihypertensive vasodilator drug. We… (More)
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