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Titration Study

Known as: DOSE ESCALATION, Rising Dose 
A study in which the dosage of the intervention is increased by small increments until the desired physiological effect is seen.
National Institutes of Health

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Clinical Data Interchange Standards Consortium TerminologyTitration Method

Papers overview

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2017
2017
Imatinib dose escalation versus sunitinib as a second-line treatment against advanced gastrointestinal stromal tumors: A nationwide population-based cohort study
Background Although treatment with imatinib in advanced gastrointestinal stromal tumor (GIST) patients has led to significant… 
2016
2016
Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study
The outcomes for patients with esophageal cancer (EC) underwent standard-dose radical radiotherapy were still disappointing. This… 
Review
2016
Review
2016
Implanted spacer approaches for pelvic radiation therapy
ABSTRACT Introduction: Recent clinical advances in radiation therapy have aimed to improve the therapeutic ratio through… 
2014
2014
Effect of [(18)F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice.
2014
2014
Long-term durability and dose escalation patterns in infliximab therapy for psoriasis.
2014
2014
Is intermediate radiation dose escalation with concurrent chemotherapy for stage III non-small-cell lung cancer beneficial? A multi-institutional propensity score matched analysis.
2014
2014
Current controversies in radiotherapy for nasopharyngeal carcinoma (NPC).
2013
2013
Preliminary Safety and Efficacy Of IPI-145, a Potent Inhibitor Of Phosphoinositide-3-Kinase-δ,γ, In Patients With Chronic Lymphocytic Leukemia
Introduction IPI-145 is an oral, potent PI3K-δ,γ inhibitor currently in development for the treatment of hematologic (heme… 
Review
2012
Review
2012
Radiation treatment for patients with intermediate-risk prostate cancer
Around 70% of men presenting with prostate cancer will have organ-confined disease, with the majority presenting with low- or… 
2008
2008
A phase I dose escalation (DE) and pharmacokinetics (PK) study of intravenous aflibercept (VEGF Trap) plus irinotecan, 5-fluorouracil, and leucovorin (I-LV5FU2) in patients with advanced solid tumors…
3557 Background: Aflibercept (AF), a recombinant fusion molecule of the human VEGF receptor extracellular domains and the Fc… 
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