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Tissue Slice Technology

A technology used for preclinical research as an alternative to some animal testing. Micrometer-thin slices of various organs are incubated with… 
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis.
2018
2018
An ex vivo Tissue Culture Model for the Assessment of Individualized Drug Responses in Prostate and Bladder Cancer
Urological malignancies, including prostate and bladder carcinoma, represent a major clinical problem due to the frequent… 
2006
2006
An ex vivo human model system to evaluate specificity of replicating and non‐replicating gene therapy agents
Inefficiency, aspecificity and toxicity of gene transfer vectors hamper gene therapy from showing its full potential. On this… 
2005
2005
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system
IntroductionIn view of the limited success of available treatment modalities for metastatic breast cancer, alternative and… 
1997
1997
Two‐dimensional electrophoresis of precision‐cut testis slices: Toxicologic application
Advances in tissue slice technology and a recent novel application of this technique to reproductive toxicology using bovine… 
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