Thymic epithelial cell

Known as: TEC, Epithlelial cell of thymus gland, Epithelial reticular cell 
A reticular epithelial cell generated in the thymus that affects T-lymphocyte cell production. Thymic epithelial cells are organized in a three… (More)
National Institutes of Health

Papers overview

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Review
2012
Review
2012
The thymus represents an epithelial-mesenchymal tissue, anatomically structured into discrete cortical and medullary regions that… (More)
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Highly Cited
2010
Highly Cited
2010
The thymus is essential for T-cell development. Here, we focus on the role of the transcription factor Foxn1 in the development… (More)
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Highly Cited
2009
Highly Cited
2009
Central tolerance is shaped by the array of self-antigens expressed and presented by various types of thymic antigen-presenting… (More)
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Highly Cited
2009
Highly Cited
2009
In the thymus, interactions between immature thymocytes and thymic epithelial cells (TECs) regulate the development and selection… (More)
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Highly Cited
2008
Highly Cited
2008
Medullary thymic epithelial cells (mTECs) are specialized for inducing central immunological tolerance to self-antigens. To… (More)
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Highly Cited
2007
Highly Cited
2007
The systemic administration of keratinocyte growth factor (KGF) enhances T-cell lymphopoiesis in normal mice and mice that… (More)
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Highly Cited
2003
Highly Cited
2003
Thymic epithelial cells (TECs) are required for T cell maturation within the thymus. In the nude (Foxn1nu/nu) mouse, TECs fail to… (More)
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Highly Cited
2002
Highly Cited
2002
T cell differentiation and repertoire selection depend critically on several distinct thymic epithelial cell types, whose lineage… (More)
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Highly Cited
2002
Highly Cited
2002
Decreased thymopoietic capacity contributes to the severe and clinically significant immune deficiency seen after bone marrow… (More)
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Highly Cited
1998
Highly Cited
1998
Thymocyte and thymic epithelial cell (TEC) development are interdependent processes. Although lineage relationships among… (More)
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