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Thymic epithelial cell

Known as: TEC, Epithlelial cell of thymus gland, Epithelial reticular cell 
A reticular epithelial cell generated in the thymus that affects T-lymphocyte cell production. Thymic epithelial cells are organized in a three… 
National Institutes of Health

Related topics

Related topics

40 relations
Combined Thymic Epithelial NeoplasmEctopic Cervical ThymomaEncapsulated ThymomaEpithelium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells
T cell development and selection are coordinated in the thymus by a specialized niche of diverse stromal populations1–3. Although… 
Review
2012
Review
2012
Thymic epithelial cells: working class heroes for T cell development and repertoire selection.
Highly Cited
2011
Highly Cited
2011
Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence
The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic… 
Highly Cited
2009
Highly Cited
2009
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
Central tolerance is shaped by the array of self-antigens expressed and presented by various types of thymic antigen-presenting… 
Highly Cited
2007
Highly Cited
2007
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells.
The systemic administration of keratinocyte growth factor (KGF) enhances T-cell lymphopoiesis in normal mice and mice that… 
Highly Cited
2002
Highly Cited
2002
Generation of a complete thymic microenvironment by MTS24+ thymic epithelial cells
The epithelial component of the thymic microenvironment is indispensable for the generation of T lymphocytes. Although the… 
Highly Cited
2002
Highly Cited
2002
Identification and characterization of thymic epithelial progenitor cells.
Review
2000
Review
2000
Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation.
In the mature thymus, thymocyte maturation depends on interactions with different thymic epithelial subtypes in a three… 
Highly Cited
1998
Highly Cited
1998
Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment.
Thymocyte and thymic epithelial cell (TEC) development are interdependent processes. Although lineage relationships among… 
Highly Cited
1995
Highly Cited
1995
Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells
Thymic epithelial cells play a crucial role in the selection of developing thymocytes. Thymocyte-epithelial cell interactions… 
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