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Thymic Damage

Anatomic injury or physiologic dysfunction of the thymus gland.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration
BMP4 produced by endothelial cells promotes thymic regeneration after acute damage by activating FOXN1 and its downstream targets… 
Review
2017
Review
2017
Cytokine mediators of chronic graft-versus-host disease.
Substantial preclinical and clinical research into chronic graft-versus-host disease (cGVHD) has come to fruition in the last… 
2009
2009
Single Cell Analysis of Complex Thymus Stromal Cell Populations: Rapid Thymic Epithelia Preparation Characterizes Radiation Injury
Thymic epithelial cells (TECs) and dendritic cells are essential for the maintenance of thymopoiesis. Because these stromal… 
2009
2009
Flt3 ligand–receptor interaction is important for maintenance of early thymic progenitor numbers in steady‐state thymopoiesis
T‐cell production throughout life depends on efficient colonization and intrathymic expansion of BM‐derived hematopoietic… 
Highly Cited
2007
Highly Cited
2007
Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice.
2001
2001
Unrelated cord blood transplantion in a Fanconi anemia patient using fludarabine-based conditioning
Unrelated cord blood transplantion in a Fanconi anemia patient using fludarabine-based conditioning 
Highly Cited
2000
Highly Cited
2000
Graft-versus-host-disease-associated thymic damage results in the appearance of T cell clones with anti-host reactivity.
BACKGROUND We studied whether T-cell clones, which appear in the periphery as a result of the failure of thymic negative… 
Highly Cited
1998
Highly Cited
1998
Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via In utero or postnatal transfer.
Although in utero transplantation (IUT) has been shown to be effective in treating human severe combined immune deficiency (SCID… 
Review
1996
Review
1996
Posttransfusion graft‐versus‐host disease in Japanese newborns
BACKGROUND: Posttransfusion graft‐versus‐host disease (PT‐GVHD) is underdiagnosed and underreported. Risk factors predisposing to… 
Highly Cited
1987
Highly Cited
1987
Pathology of the thymus after allogeneic bone marrow transplantation in man. A histologic immunohistochemical study of 36 patients.
A major hypothesis to explain the immunodeficiency associated with bone marrow transplantation states that thymic epithelial… 
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