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Threonine Tyrosine Kinase Inhibitor CFI-402257

Known as: CFI-402257, TTK Inhibitor CFI-402257, MSP1 Inhibitor CFI-402257 
An orally bioavailable, selective inhibitor of the dual specificity protein kinase TTK (monopolar spindle 1 kinase, Mps1), with potential… 
National Institutes of Health

Papers overview

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2020
2020
Abstract PD2-03: CDK4/6 inhibitor-resistant ER+ breast cancer cell lines are hypersensitive to TTK inhibition
Inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6i), in combination with hormonal therapies, have become standard of care… 
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