FAQ

Technetium Tc 99m-3PRGD2

Known as: (99m)Tc-PEG(4)-E[PEG(4)-c(RGDfK)](2) ((99m)Tc-3PRGD2), 99mTc-3PRGD2 
A radiopharmaceutical agent comprised of a pegylated arginine-glycine-aspartic acid (RGD) dimer (PRGD2) labeled with technetium Tc 99m, with… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2018
012320102018

Papers overview

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2017
2017
Early detection of rheumatoid arthritis in rats and humans with 99mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis
OBJECTIVES To validate 99mTc-labeled arginylglycylaspartic acid (99mTc-3PRGD2) scintigraphy as a means to image synovial… (More)
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2016
2016
Integrin Imaging with 99mTc-3PRGD2 SPECT/CT Shows High Specificity in the Diagnosis of Lymph Node Metastasis from Non-Small Cell Lung Cancer.
Purpose To evaluate an integrin imaging approach based on single photon emission computed tomography (SPECT)/computed tomography… (More)
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2015
2015
99mTc-3PRGD2 SPECT to monitor early response to neoadjuvant chemotherapy in stage II and III breast cancer
Monitoring of response to neoadjuvant chemotherapy (NCT) is important for optimal management of patients with breast cancer… (More)
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2014
2014
Longitudinal monitoring of tumor antiangiogenic therapy with near-infrared fluorophore-labeled agents targeted to integrin αvβ3 and vascular endothelial growth factor
Optical imaging is emerging as a powerful tool for the noninvasive imaging of the biological processes in living subjects. This… (More)
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2014
2014
Comparison of 99mTc-3PRGD2 Integrin Receptor Imaging with 99mTc-MDP Bone Scan in Diagnosis of Bone Metastasis in Patients with Lung Cancer: A Multicenter Study
PURPOSE 99mTc-3PRGD2, a promising tracer targeting integrin receptor, may serve as a novel tumor-specific agent for single photon… (More)
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Review
2014
Review
2014
99mTc-3PRGD2 Scintimammography in Palpable and Nonpalpable Breast Lesions.
The aim of this study was to explore the diagnostic performance of 99mTc-3(poly-(ethylene glycol),PEG)4-RGD2 (99mTc-3PRGD2… (More)
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2012
2012
99mTc-3PRGD2 for integrin receptor imaging of lung cancer: a multicenter study.
UNLABELLED (99m)Tc-3PRGD2 is a new SPECT tracer targeting integrin α(V)β(3) receptor for detecting tumors, imaging angiogenesis… (More)
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2012
2012
Integrin αvβ3 imaging of radioactive iodine-refractory thyroid cancer using 99mTc-3PRGD2.
UNLABELLED Integrin α(v)β(3) has been proposed as a potential imaging target for radiolabeled RGD peptides and a molecular marker… (More)
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2012
2012
Noninvasive Detection of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Teratoma with an Integrin-Targeting Agent 99mTc-3PRGD2
Since their discovery in 2006, induced pluripotent stem cells (iPSCs) have gained increasing interest for tissue regeneration and… (More)
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2010
2010
Blood Clearance Kinetics, Biodistribution, and Radiation Dosimetry of a Kit-Formulated Integrin αvβ3-Selective Radiotracer 99mTc-3PRGD2 in Non-Human Primates
99mTc-3PRGD2 is a 99mTc-labeled dimeric cyclic RGD peptide with increased receptor binding affinity and improved kinetics for in… (More)
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