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Technetium Tc 99m-3PRGD2

Known as: (99m)Tc-PEG(4)-E[PEG(4)-c(RGDfK)](2) ((99m)Tc-3PRGD2), 99mTc-3PRGD2 
A radiopharmaceutical agent comprised of a pegylated arginine-glycine-aspartic acid (RGD) dimer (PRGD2) labeled with technetium Tc 99m, with… 
National Institutes of Health

Papers overview

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2017
2017
Clinical Value of 99mTc-3PRGD2 SPECT/CT in Differentiated Thyroid Carcinoma with Negative 131I Whole-Body Scan and Elevated Thyroglobulin Level
The aim of this study was to assess the usefulness of integrin imaging with 99mTc-PEG4-E[PEG4-c(RGDfK)]2 (99mTc-3PRGD2) single… 
2017
2017
Early detection of rheumatoid arthritis in rats and humans with 99mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis
Objectives: To validate 99mTc-labeled arginylglycylaspartic acid (99mTc-3PRGD2) scintigraphy as a means to image synovial… 
2017
2017
Evaluation of 99mTc-3PRGD2 integrin receptor imaging in hepatocellular carcinoma tumour-bearing mice: comparison with 18F-FDG metabolic imaging
ObjectiveOur study was designed to explore the utility of 99mTc-HYNIC-PEG4-E[PEG4-c(RGDfK)]2 (99mTc-3PRGD2) for the detection of… 
2015
2015
99mTc-3PRGD2 SPECT/CT predicts the outcome of advanced nonsquamous non-small cell lung cancer receiving chemoradiotherapy plus bevacizumab
BackgroundFunctional imaging can help clinicians assess the individual response of advanced nonsquamous non-small cell lung… 
2015
2015
Biometabolic Distribution of 99mTc-3PRGD2 and its Potential Value in Monitoring Chemotherapeutic Effects
Previous studies have reported that 99mTc-3PRGD2 is an excellent tumor imaging agent that showed a good correlation with integrin… 
Review
2014
Review
2014
99mTc-3PRGD2 Scintimammography in Palpable and Nonpalpable Breast Lesions
The aim of this study was to explore the diagnostic performance of 99mTc-3(poly-(ethylene glycol),PEG)4-RGD2 (99mTc-3PRGD2… 
Review
2014
Review
2014
(99)mTc-3PRGD2 scintimammography in palpable and nonpalpable breast lesions.
The aim of this study was to explore the diagnostic performance of 99mTc-3(poly-(ethylene glycol),PEG)4-RGD2 (99mTc-3PRGD2… 
2012
2012
Integrin αvβ3 Imaging of Radioactive Iodine–Refractory Thyroid Cancer Using 99mTc-3PRGD2
Integrin αvβ3 has been proposed as a potential imaging target for radiolabeled RGD peptides and a molecular marker for the… 
2012
2012
Noninvasive Detection of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Teratoma with an Integrin-Targeting Agent 99mTc-3PRGD2
PurposeSince their discovery in 2006, induced pluripotent stem cells (iPSCs) have gained increasing interest for tissue… 
Highly Cited
2010
Highly Cited
2010
Blood Clearance Kinetics, Biodistribution, and Radiation Dosimetry of a Kit-Formulated Integrin αvβ3-Selective Radiotracer 99mTc-3PRGD2 in Non-Human Primates
Purpose99mTc-3PRGD2 is a 99mTc-labeled dimeric cyclic RGD peptide with increased receptor binding affinity and improved kinetics… 
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