TZP-101

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2015
012320072015

Papers overview

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2011
2011
BACKGROUND Limited therapeutic options exist for severe gastroparesis, where severe nausea and vomiting can lead to weight loss… (More)
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2011
2011
High-throughput screening of Tranzyme Pharma's proprietary macrocycle library using the aequorin Ca2+-bioluminescence assay… (More)
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2010
2010
BACKGROUND Gastroparesis, a chronic disorder of abnormal gastric motility, is common in patients with diabetes mellitus. A… (More)
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2010
2010
PURPOSE Ghrelin agonist TZP-101 is a potent prokinetic. This phase 2b study evaluated TZP-101 safety and efficacy in… (More)
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2009
2009
BACKGROUND TZP-101 is a synthetic, selective ghrelin agonist in development for gastroparesis. AIM To assess safety and effects… (More)
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2009
2009
Ghrelin, the natural ligand of the growth hormone secretagogue receptor (ghrelin receptor), is an orexigenic gut hormone with… (More)
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2009
2009
BACKGROUND AND OBJECTIVE TZP-101 is a selective, small molecule ghrelin receptor agonist in clinical development for the… (More)
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2008
2008
The authors evaluate the human safety, tolerability, pharmacokinetics, and pharmacodynamics of TZP-101, an agonist of the hGHS… (More)
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2008
2008
The peptide hormone ghrelin exerts a wide spectrum of activities including the stimulation of GH release, feeding, and… (More)
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2007
2007
Postoperative ileus (POI) is a major cause of postoperative complications and prolonged hospitalization. Ghrelin, which is the… (More)
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