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TYRP1 gene

Known as: TYRP, Tyrosinase-Related Protein 1 Gene, OCA3 
This gene plays a role in melanogenesis and sensory transduction/vision.
National Institutes of Health

Related topics

Related topics

8 relations
ALBINISM, OCULOCUTANEOUS, TYPE IIIMelanogenesisOxidation-ReductionRecombinant Tyrosinase-Related Protein-1

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TYRP1 wt Allele

Papers overview

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Highly Cited
2015
Highly Cited
2015
Foreign DNA acquisition by the I-F CRISPR–Cas system requires all components of the interference machinery
CRISPR immunity depends on acquisition of fragments of foreign DNA into CRISPR arrays. For type I-E CRISPR–Cas systems two modes… 
Highly Cited
2013
Highly Cited
2013
In Silico Screening and Molecular Dynamics Simulation of Disease-Associated nsSNP in TYRP1 Gene and Its Structural Consequences in OCA3
Oculocutaneous albinism type III (OCA3), caused by mutations of TYRP1 gene, is an autosomal recessive disorder characterized by… 
Review
2003
Review
2003
Vertebrate and invertebrate TRPV-like mechanoreceptors.
Highly Cited
2003
Highly Cited
2003
TYRP1 is associated with dun coat colour in Dexter cattle or how now brown cow?
Tyrosinase related protein 1 (TYRP1), which is involved in the coat colour pathway, was mapped to BTA8 between microsatellites… 
Highly Cited
2002
Highly Cited
2002
TYRP1 and MC1R genotypes and their effects on coat color in dogs
We used PCR amplification of cDNA prepared from skin biopsies to determine the nearly full-length, protein-coding sequence of dog… 
Highly Cited
2001
Highly Cited
2001
Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus)
Abstract. Coat color genetics, when successfully adapted and applied to different mammalian species, provides a good… 
Highly Cited
1997
Highly Cited
1997
Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene.
Oculocutaneous albinism (OCA) is the most common autosomal recessive disorder among southern African Blacks. There are three… 
Highly Cited
1995
Highly Cited
1995
Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes [published erratum appears in J Exp Med 1995 Mar 1;181(3):1261]
The availability of antitumor cytotoxic T lymphocytes which can be generated from either peripheral blood lymphocytes after… 
Highly Cited
1995
Highly Cited
1995
Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family.
The structures of the human tyrosinase-related protein genes TYRP1 and TYRP2 have been determined and compared with that of the… 
Highly Cited
1993
Highly Cited
1993
In vitro and in vivo targeting of gene expression to melanoma cells.
Gene therapy protocols for cancer usually involve removal of tumor cells, culture in vitro to allow gene transfer, and subsequent… 
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