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TY 51469
Known as:
TY-51469
, TY51469
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Sulfonamides
Thiophenes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Chymase inhibitor TY-51469 in therapy of inflammatory bowel disease.
Wei-xin Liu
,
Ying Wang
,
+4 authors
Shou-Zhi Gu
World Journal of Gastroenterology
2016
Corpus ID: 41922434
AIM To investigate the effect of chymase inhibitor TY-51469 in the therapy of inflammatory bowel disease and the underlying…
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2016
2016
Effect of TY-51469 on macrophage pattern in mice subjected fatigue exercise
Ma Xinli
,
Chen Yichen
,
+13 authors
C. Guangjie
2016
Corpus ID: 115251713
2014
2014
Chymase inhibition improves vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats
S. Takai
,
D. Jin
,
+7 authors
H. Okamura
Journal of Hypertension
2014
Corpus ID: 5899565
Objective: To clarify the role of chymase in hypertension, we evaluated the effect of a chymase inhibitor, TY-51469, on vascular…
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2014
2014
Chymase Inhibition Attenuates Lipopolysaccharide/ D-Galactosamine-Induced Acute Liver Failure in Hamsters
Yoshiro Imai
,
S. Takai
,
+7 authors
K. Uchiyama
Pharmacology
2014
Corpus ID: 6121746
Background/Aims: Chymase inhibition has been shown to attenuate matrix metalloproteinase (MMP)-9 and tumor necrosis factor (TNF…
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2013
2013
Chymase inhibitor ameliorates hepatic steatosis and fibrosis on established non‐alcoholic steatohepatitis in hamsters fed a methionine‐ and choline‐deficient diet
S. Masubuchi
,
S. Takai
,
+7 authors
K. Uchiyama
Hepatology Research
2013
Corpus ID: 31925400
Chymase plays a role in the augmentation of angiotensin II formation, which is involved in liver fibrosis. The therapeutic…
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2012
2012
Cisplatin-induced acute renal failure in mice is mediated by chymase-activated angiotensin-aldosterone system and interleukin-18.
Shin Okui
,
Hideyuki Yamamoto
,
+9 authors
H. Ueda
European Journal of Pharmacology
2012
Corpus ID: 6545285
2012
2012
Effect of chymase inhibitors on dimethylnitrosamine- induced rat liver fibrosis and on chymase and collagen I expression
M. Yin
,
Shi-Ying Jin
,
Hesong Cui
2012
Corpus ID: 54821073
Chymase converts angiotensin (Ang) I to Ang II, which may promote the development of liver fibrosis. In this study, a chymase…
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2010
2010
The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice
髙戸 葉月
2010
Corpus ID: 87059739
2009
2009
Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes.
S. Takai
,
D. Jin
,
M. Ohzu
,
Kazuhiko Tanaka
,
M. Miyazaki
Journal of Pharmacological Sciences
2009
Corpus ID: 20544948
Angiotensin II may be involved in pancreatic disorganization, but the involvement of chymase has been unclear. In the present…
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2009
2009
S1607 A Specific Chymase Inhibitor TY-51469 Suppressed Tetrachloride-Induced Liver Fibrosis in a Hamster Model
K. Koji
,
D. Jin
,
+4 authors
M. Mizuo
2009
Corpus ID: 73385262
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