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TTYH1 gene

Known as: TTYH1, TWEETY, DROSOPHILA, HOMOLOG OF, 1, tweety family member 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
TTYH1 and TTYH2 Serve as LRRC8A-Independent Volume-Regulated Anion Channels in Cancer Cells
Volume-regulated anion channels (VRACs) are involved in cellular functions such as regulation of cell volume, proliferation… 
2018
2018
Ttyh1 regulates embryonic neural stem cell properties by enhancing the Notch signaling pathway
Despite growing evidence linking Drosophila melanogaster tweety‐homologue 1 (Ttyh1) to normal mammalian brain development and… 
2017
2017
Expression and purification of mouse Ttyh1 fragments as antigens to generate Ttyh1-specific monoclonal antibodies.
Highly Cited
2013
Highly Cited
2013
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain tumors characterized by high-level… 
2010
2010
Ttyh1, a Ca2+‐binding protein localized to the endoplasmic reticulum, is required for early embryonic development
Using comprehensive genetic studies on neuronal stem/progenitors cells through genome‐wide screening with oligonucleotide arrays… 
2010
2010
Expression of Ttyh1, a member of the Tweety family in neurons in vitro and in vivo and its potential role in brain pathology
J. Neurochem. (2010) 115, 1183–1194. 
2008
2008
The Ubiquitin-Protein Ligase Nedd4-2 Differentially Interacts with and Regulates Members of the Tweety Family of Chloride Ion Channels*
The Tweety proteins comprise a family of chloride ion channels with three members identified in humans (TTYH1-3) and orthologues… 
2008
2008
N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety…
The Tweety proteins are a family of recently identified putative Cl(-) channels predicted to be modified by N-glycosylation and… 
2007
2007
Expression and evolution of the mammalian brain gene Ttyh1
Homologues of the Drosophila melanogaster tweety (tty) gene are present in mammals and Caenorhabditis elegans. The encoded… 
2000
2000
Human and mouse homologues of the Drosophila melanogaster tweety (tty) gene: a novel gene family encoding predicted transmembrane proteins.
We have cloned cDNA for TTYH1, a human homologue of the Drosophila melanogaster tweety (tty) gene. The 450-residue predicted… 
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