TRX1 drug

Known as: TRX1 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
RATIONALE Thioredoxin (Trx)1 inhibits pathological cardiac hypertrophy. MicroRNAs (miRNAs) are small noncoding RNAs that… (More)
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Highly Cited
2008
Highly Cited
2008
The mammalian cytosolic/nuclear thioredoxin system, comprising thioredoxin (Trx), selenoenzyme thioredoxin reductase (TrxR), and… (More)
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2006
2006
In this study we investigate the effect of thioredoxin (Trx1) protein fusions in the production, oxidation, and folding of single… (More)
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Highly Cited
2006
Highly Cited
2006
Tumor necrosis factor-alpha (TNF-alpha) is a cytokine that is involved in numerous pathologies, in part through stimulation of… (More)
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Highly Cited
2005
Highly Cited
2005
Exogenously added ROS (reactive oxygen species) cause generalized oxidation of cellular components, whereas endogenously… (More)
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Highly Cited
2004
Highly Cited
2004
Redox mechanisms function in control of gene expression, cell proliferation, and apoptosis, but the circuitry for redox signaling… (More)
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Highly Cited
2002
Highly Cited
2002
Oxidative damage to mitochondria is a central mechanism of apoptosis induced by many toxic chemicals. Thioredoxin family proteins… (More)
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Highly Cited
2000
Highly Cited
2000
We examined the in vivo expression of up to 16 genes encoding for components of both glutaredoxin and thioredoxin systems and for… (More)
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Highly Cited
1999
Highly Cited
1999
Reduction of inorganic sulfate to sulfite in prototrophic bacteria occurs with 3'-phosphoadenylylsulfate (PAPS) as substrate for… (More)
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Highly Cited
1997
Highly Cited
1997
We have isolated a 1276-base pair cDNA from a rat heart cDNA library that encodes a novel thioredoxin (Trx2) of 166 amino acid… (More)
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