TRU 016

CD37 is cell surface tetraspanin present on normal and malignant B cells. Otlertuzumab (TRU-016) is a novel humanized anti-CD37… Expand

SummaryPurpose CD37 is cell surface tetraspanin present on normal and malignant B cells. Otlertuzumab (TRU-016) is a novel… Expand

Monoclonal antibodies (mAbs) - rituximab, ofatumumab and alemtuzumab - have been approved for use in the therapy of chronic… Expand

Abstract 1792 Background: CD37 is a tetraspanin protein expressed on the surface of normal and transformed B-cells across a wide… Expand

Abstract 56 Background: CD37 is a member of the tetraspanin superfamily of molecules which are implicated in diverse processes… Expand

Abstract 3931 Background: CD37 is a 50–55 kDa heavily glycosylated member of the tetraspanin superfamily of molecules. This cell… Expand

TRU-016, under development by Trubion Pharmaceuticals Inc and Facet Biotech Corp, is an intravenously administered anti-CD37 IgG… Expand

8571 Background: TRU-016, a single chain anti-CD37 Fc fusion molecule has been shown to display pro-apoptotic and Fc-dependent… Expand

3017 Background: CD37 is a tetraspan family member expressed predominantly on normal and transformed B-cells across a wide range… Expand

Abstract 3424 Poster Board III-312 Background CD37 is a tetraspanin family member expressed predominantly on normal and… Expand