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TRU 016
Known as:
TRU-016
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Immunoglobulin G
Recombinant Fusion Proteins
Narrower (1)
otlertuzumab
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Randomized phase 2 study of otlertuzumab and bendamustine versus bendamustine in patients with relapsed chronic lymphocytic leukaemia
T. Robak
,
A. Hellmann
,
+13 authors
U. Jaeger
British journal of haematology
2017
Corpus ID: 14967513
Otlertuzumab (TRU‐016) is a humanized anti‐CD37 protein therapeutic that triggers direct caspase‐independent apoptosis of…
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2015
2015
Otlertuzumab (TRU‐016), an anti‐CD37 monospecific ADAPTIR™ therapeutic protein, for relapsed or refractory NHL patients
J. Pagel
,
S. Spurgeon
,
+6 authors
A. Gopal
British journal of haematology
2015
Corpus ID: 207082824
CD37 is cell surface tetraspanin present on normal and malignant B cells. Otlertuzumab (TRU‐016) is a novel humanized anti‐CD37…
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2014
2014
Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR™ therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients
A. Gopal
,
S. Tarantolo
,
+7 authors
A. Goy
Investigational New Drugs
2014
Corpus ID: 41847548
SummaryPurpose CD37 is cell surface tetraspanin present on normal and malignant B cells. Otlertuzumab (TRU-016) is a novel…
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2013
2013
Phase 2 Study Of Otlertuzumab (TRU-016), An Anti-CD37 ADAPTIRTM Protein, In Combination With Bendamustine Vs Bendamustine Alone In Patients With Relapsed Chronic Lymphocytic Leukemia (CLL)
T. Robak
,
A. Hellman
,
+11 authors
J. Kłoczko
2013
Corpus ID: 74167849
Background CD37 is a tetraspanin protein expressed on the surface of normal and transformed B-cells across a wide range of…
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2010
2010
Phase 1 Dose Escalation Study of TRU-016, An Anti-CD37 SMIP™ Protein In Relapsed and Refractory CLL
R. Furman
,
L. Andritsos
,
+6 authors
J. Byrd
2010
Corpus ID: 208412361
Abstract 56 Background: CD37 is a member of the tetraspanin superfamily of molecules which are implicated in diverse processes…
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2010
2010
TRU-016, An Anti-CD37 SMIP™ Biologic, In Combination with Other Therapeutic Drugs In Models of Non-Hodgkin's Lymphoma
P. Algate
,
J. Wiens
,
+5 authors
B. Gordon
2010
Corpus ID: 78201906
Abstract 3931 Background: CD37 is a 50–55 kDa heavily glycosylated member of the tetraspanin superfamily of molecules. This cell…
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Review
2009
Review
2009
TRU-016, a humanized anti-CD37 IgG fusion protein for the potential treatment of B-cell malignancies.
T. Robak
,
P. Robak
,
P. Smolewski
Current opinion in investigational drugs
2009
Corpus ID: 22118224
TRU-016, under development by Trubion Pharmaceuticals Inc and Facet Biotech Corp, is an intravenously administered anti-CD37 IgG…
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2009
2009
Evaluation of the effect of TRU-016, an anti-CD37 directed SMIP in combination with other therapeutic drugs in models of non-Hodgkin's lymphoma.
P. Baum
,
C. Cerveny
,
+7 authors
A. Wahl
Journal of clinical oncology : official journal…
2009
Corpus ID: 36447451
8571 Background: TRU-016, a single chain anti-CD37 Fc fusion molecule has been shown to display pro-apoptotic and Fc-dependent…
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2009
2009
A phase I trial of TRU-016, an anti-CD37 small modular immunopharmaceutical (SMIP) in relapsed and refractory CLL.
L. Andritsos
,
R. Furman
,
+4 authors
J. Byrd
Journal of clinical oncology : official journal…
2009
Corpus ID: 34796764
3017 Background: CD37 is a tetraspan family member expressed predominantly on normal and transformed B-cells across a wide range…
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2009
2009
A Phase 1 Trial of TRU-016, An Anti-CD37 Small Modular Immunopharmaceutical (SMIPTM) Protein in Relapsed and Refractory CLL: Early Promising Clinical Activity.
L. Andritsos
,
R. Furman
,
+6 authors
J. Byrd
2009
Corpus ID: 78219135
Abstract 3424 Poster Board III-312 Background CD37 is a tetraspanin family member expressed predominantly on normal and…
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