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TRIM6 gene

Known as: TRIM6, tripartite motif containing 6, TRIPARTITE MOTIF-CONTAINING PROTEIN 6 
National Institutes of Health

Related topics

Related topics

1 relation
TRIM7 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
E3-ubiquitin ligase TRIM6 aggravates myocardial ischemia/reperfusion injury via promoting STAT1-dependent cardiomyocyte apoptosis
Cardiomyocyte apoptosis is a major cause of myocardial ischemia/reperfusion (MI/R) injury, in which the activation of the signal… 
2018
2018
Characterization of WDR20: A new regulator of the ERAD machinery.
Highly Cited
2016
Highly Cited
2016
The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I… 
Highly Cited
2014
Highly Cited
2014
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response.
2014
2014
Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.
2013
2013
Elevated Rate of Fixation of Endogenous Retroviral Elements in Haplorhini TRIM5 and TRIM22 Genomic Sequences: Impact on Transcriptional Regulation
All genes in the TRIM6/TRIM34/TRIM5/TRIM22 locus are type I interferon inducible, with TRIM5 and TRIM22 possessing antiviral… 
2012
2012
TRIM6 interacts with Myc and maintains the pluripotency of mouse embryonic stem cells
The proto-oncogene product Myc is a master regulator of cell proliferation through its specific binding to the E-box motif in… 
2012
2012
TRIM genes are part of the interferon signature observed in patients with primary Sjögren's syndrome
Background and objectives Autoimmune disease can arise when the immune system is overactive in response to a trigger. This… 
2007
2007
Unique features of TRIM5alpha among closely related human TRIM family members.
The tripartite motif (TRIM) protein, TRIM5alpha, restricts some retroviruses, including human immunodeficiency virus (HIV-1… 
Highly Cited
2006
Highly Cited
2006
Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.
Primate tripartite motif 5alpha (TRIM5alpha) proteins mediate innate intracellular resistance to retroviruses. In humans, TRIM5… 
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