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TRIM2 gene

Known as: RNF86, KIAA0517, TRIPARTITE MOTIF-CONTAINING PROTEIN 2 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
0120012017

Papers overview

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2017
2017
GPER promotes tamoxifen-resistance in ER+ breast cancer cells by reduced Bim proteins through MAPK/Erk-TRIM2 signaling axis.
Tamoxifen resistance is a major clinical challenge in breast cancer treatment. Our previous studies find that GPER and its down… (More)
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2015
2015
MicroRNA-145 targets TRIM2 and exerts tumor-suppressing functions in epithelial ovarian cancer.
OBJECTIVE Epithelial ovarian cancer (EOC) is one of the most common cancers in women worldwide but relatively little is known… (More)
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2014
2014
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal NHL domain of human TRIM2.
The tripartite motif-containing protein 2 (TRIM2) functions as an E3 ubiquitin ligase. Loss of function of TRIM2 has been shown… (More)
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2013
2013
Deficiency of the E3 ubiquitin ligase TRIM2 in early-onset axonal neuropathy.
Inherited peripheral neuropathies are a heterogeneous group of disorders that can affect patients of all ages. Children with… (More)
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2011
2011
Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β
MicroRNAs (miRNAs) are small non-coding RNA regulators of protein synthesis that are essential for normal brain development and… (More)
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2008
2008
Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration.
TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in the pathogenesis of some human… (More)
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2001
2001
Fundamental Issues in Computer Design and Implementation for the Socioeconomic Microsimulation Community
ation of the RIM model [Wilensky 1970] for use by the President's Commission in Income Maintenance in the United States. RIM… (More)
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