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TRIM2 gene

Known as: RNF86, KIAA0517, TRIPARTITE MOTIF-CONTAINING PROTEIN 2 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
TRIM2 directly deubiquitinates and stabilizes Snail1 protein, mediating proliferation and metastasis of lung adenocarcinoma
Background Lung adenocarcinoma has surpassed lung squamous cell carcinoma as the most common type of non-small cell lung cancer… Expand
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2018
2018
TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival
Background and aim Tripartite motif containing (TRIM) family protein has been involved in multiple pathogenesis of cancers. TRIM2… Expand
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2015
2015
MicroRNA-145 targets TRIM2 and exerts tumor-suppressing functions in epithelial ovarian cancer.
OBJECTIVE Epithelial ovarian cancer (EOC) is one of the most common cancers in women worldwide but relatively little is known… Expand
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2014
2014
Expression, purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal NHL domain of human TRIM2.
The tripartite motif-containing protein 2 (TRIM2) functions as an E3 ubiquitin ligase. Loss of function of TRIM2 has been shown… Expand
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2014
2014
Response to Belgard et al.
Correction to: Molecular Psychiatry (2014) advance online publication 14 January 2014; doi:10.1038/mp.2013.186 Following… Expand
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Highly Cited
2013
Highly Cited
2013
Deficiency of the E3 ubiquitin ligase TRIM2 in early-onset axonal neuropathy.
Inherited peripheral neuropathies are a heterogeneous group of disorders that can affect patients of all ages. Children with… Expand
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2013
2013
O42 – 1909 FOXG1 gene: phenotype–genotype relation in Spanish patients
Purpose: To reveal the genetic etiology of an early-onset axonal neuropathy. Patient: Our patient is a 19-year-old female with… Expand
Highly Cited
2011
Highly Cited
2011
Target Gene Repression Mediated by miRNAs miR-181c and miR-9 Both of Which Are Down-regulated by Amyloid-β
MicroRNAs (miRNAs) are small non-coding RNA regulators of protein synthesis that are essential for normal brain development and… Expand
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Highly Cited
2008
Highly Cited
2008
Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration
TRIM RING finger proteins have been shown to play an important role in cancerogenesis, in the pathogenesis of some human… Expand
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2007
2007
Increased expression of ephrin A1 in brain arteriovenous malformation: DNA microarray analysis
A number of previous studies have revealed the abnormal expression of various angiogenesis-related genes or products in brain… Expand
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