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TPX2 gene

Known as: C20ORF1, TPX2, microtubule-associated, DIL-2 
This gene plays a role in the assembly of the mitotic spindle.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessGTP BindingMicrotubule Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis
In amyotrophic lateral sclerosis caused by mutations in Cu/Zn‐superoxide dismutase (SOD1), altered solubility and aggregation of… 
Highly Cited
2003
Highly Cited
2003
Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5.
Signal transducer and activator of transcription 5 (Stat5) plays a critical role in prolactin (PRL)-induced transcription of… 
Highly Cited
2003
Highly Cited
2003
NF- kappa B2/p100 induces Bcl-2 expression.
The NF-kappaB2/p100 and bcl-3 genes are involved in chromosomal translocations described in chronic lymphocytic leukemias (CLL… 
Highly Cited
1999
Highly Cited
1999
Regulation of NF-κB activity by IκB-related proteins in adenocarcinoma cells
Constitutive NF-κB activity varies widely among cancer cell lines. In this report, we studied the expression and the role of… 
Highly Cited
1999
Highly Cited
1999
The Adherence-Associated Lipoprotein P100, Encoded by an opp Operon Structure, Functions as the Oligopeptide-Binding Domain OppA of a Putative Oligopeptide Transport System in Mycoplasma hominis
ABSTRACT Mycoplasma hominis, a cell-wall-less prokaryote, was shown to be cytoadherent by the participation of a 100-kDa membrane… 
Highly Cited
1995
Highly Cited
1995
Specific inhibition of RelB/p52 transcriptional activity by the C-terminal domain of p100.
The Rel/NF-kappa B family transcriptional factors plays an important role in the regulation of immune and acute phase responses… 
Highly Cited
1994
Highly Cited
1994
Tax induces nuclear translocation of NF-kappa B through dissociation of cytoplasmic complexes containing p105 or p100 but does not induce degradation of I kappa B alpha/MAD3
The activity of the NF-kappa B transcription factor is controlled through cytoplasmic retention by either of two types of… 
Highly Cited
1989
Highly Cited
1989
Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals
The transport of proteins into the nucleus requires not only the presence of a nuclear transport signal on the targeted protein… 
Highly Cited
1981
Highly Cited
1981
Analysis of surface proteins of mouse lung carcinomas using monoclonal antibodies.
Hybridoma cultures secreting monoclonal antibodies were derived from fusions of parent myeloma P3-X63-Ag8 with spleen cells of… 
Highly Cited
1980
Highly Cited
1980
Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation
Abelson murine leukemia virus transforms both lymphoid cells and fibroblasts in vitro and induces a unique type of thymus… 
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