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TPX2 gene

Known as: C20ORF1, TPX2, microtubule-associated, DIL-2 
This gene plays a role in the assembly of the mitotic spindle.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlCell Proliferation Regulatory ProcessGTP BindingMicrotubule Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Non-canonical NF-κB signaling pathway
The non-canonical NF-κB pathway is an important arm of NF-κB signaling that predominantly targets activation of the p52/RelB NF… 
Highly Cited
2005
Highly Cited
2005
Bacteriophage P100 for control of Listeria monocytogenes in foods: genome sequence, bioinformatic analyses, oral toxicity study, and application.
Highly Cited
2003
Highly Cited
2003
Structural basis of Aurora-A activation by TPX2 at the mitotic spindle.
Highly Cited
2002
Highly Cited
2002
BAFF-induced NEMO-independent processing of NF-κB2 in maturing B cells
NF-κB is usually activated by signal-induced, ubiquitin-mediated degradation of its inhibitor, IκB. This process is initiated by… 
Highly Cited
2002
Highly Cited
2002
Human TPX2 is required for targeting Aurora-A kinase to the spindle
Aurora-A is a serine-threonine kinase implicated in the assembly and maintenance of the mitotic spindle. Here we show that human… 
Highly Cited
2000
Highly Cited
2000
Tpx2, a Novel Xenopus Map Involved in Spindle Pole Organization
TPX2, the targeting protein for Xenopus kinesin-like protein 2 (Xklp2), was identified as a microtubule-associated protein that… 
Highly Cited
1999
Highly Cited
1999
Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
Mutations of von Hippel-Lindau disease (VHL) tumor-suppressor gene product (pVHL) are found in patients with dominant inherited… 
Highly Cited
1999
Highly Cited
1999
The Rel/NF-κB signal transduction pathway: introduction
Rel/NF-kB transcription factors include a collection of proteins, conserved from Drosophila to humans (Figure 1). Among model… 
Review
1997
Review
1997
A second serine protease associated with mannan-binding lectin that activates complement
Highly Cited
1994
Highly Cited
1994
Function of Oxidative Cross-Linking of Cell Wall Structural Proteins in Plant Disease Resistance.
Elicitation of soybean cells causes a rapid insolubilization of two cell wall structural proteins, p33 and p100. Likewise, a… 
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