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TP53*1 Allele

Known as: TP53 Codon 72 Polymorphism, TP53 P72A, TP53 c.215C>G 
Human TP53*1 allele is located in the vicinity of 17p13.1 and is approximately 19 kb in length. This allele, which encodes cellular tumor antigen p53… 
National Institutes of Health

Related topics

Related topics

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17p13.1Adenocarcinoma Of EsophagusAdenocarcinoma of ampulla of VaterAdenocarcinoma of the Gastroesophageal Junction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
TP53 gene Arg72Pro polymorphism and male infertility risk: A meta‐analysis
To evaluate the association between TP53 codon72 polymorphism and male infertility risk. We conducted a search on Medline, Embase… 
2017
2017
Abstract 2153: Elephant p53 (EP53) expression induces apoptosis of human cancer cells
The goal of our study was to determine if elephant TP53 (EP53) proteins contributing to increased apoptosis and possible cancer… 
2014
2014
Estudo de polimorfismos dos genes TP53 e VEGFA como marcadores prognósticos no adenocarcinoma colorretal
2013
2013
TP53 and MDM2 Gene Polymorphisms, Gene-Gene Interaction, and Hepatocellular Carcinoma Risk: Evidence from an Updated Meta-Analysis
Background The association between TP53 R72P and/or MDM2 SNP309 polymorphisms and hepatocellular carcinoma (HCC) risk has been… 
2012
2012
Association between TP53 Arg72Pro polymorphism and hepatocellular carcinoma risk: a meta-analysis.
BACKGROUND Previous studies on the association between the TP53 Arg72Pro polymorphism and hepatocellular carcinoma (HCC) risk… 
Highly Cited
2011
Highly Cited
2011
Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Aims A study of 222 candidate genes in type 2 diabetes reported association of variants in RAPGEF1, ENPP1, TP53, NRF1, SLC2A2… 
2011
2011
Hypoxia‐inducible factor‐1α polymorphisms are associated with genetic aberrations in lung cancer
Background and objective:  The transcription factor, hypoxia‐inducible factor‐1 (HIF‐1), is a master regulator of hypoxia… 
2010
2010
Pro variant of TP53 Arg72Pro contributes to esophageal squamous cell carcinoma risk: evidence from a meta-analysis
The TP53 Arg72Pro polymorphism has been investigated as a potential genetic hallmark of esophageal cancer, but studies… 
2010
2010
Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu and the risk of lung cancer in a Japanese population.
The tumor suppressor protein p53 (TP53) plays a central role in directing cellular responses to DNA damage. Tumor protein 53… 
2009
2009
ditorial ranslating genetic questions into clinical answers in acute myeloid leukemia
  • 2009
  • Corpus ID: 13062100
The p53 tumor suppressor is central to the process by which cells ense and respond to a variety of stresses with oncogenic… 
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