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TOR signaling

Known as: TOR signaling pathway, target of rapamycin signalling pathway, TOR signaling cascade 
A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Tap46 is a regulatory subunit of a group of protein phosphatases and plays an essential role in plant cell growth and survival as… Expand
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Highly Cited
2011
Highly Cited
2011
In this paper we present a new strategy for obtaining blood vessel tissue prestress for use in fluid-structure interaction (FSI… Expand
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Highly Cited
2009
Highly Cited
2009
The nutrient-sensing target of rapamycin (TOR) pathway appears to have a conserved role in regulating life span. This signaling… Expand
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Highly Cited
2009
Highly Cited
2009
Ribosome biogenesis drives cell growth, and the large transcriptional output underlying this process is tightly regulated. The… Expand
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Highly Cited
2008
Highly Cited
2008
Degradation of cytoplasmic components by autophagy requires the class III phosphatidylinositol 3 (PI(3))–kinase Vps34, but the… Expand
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Highly Cited
2007
Highly Cited
2007
Rheb is a unique member of the Ras superfamily GTP-binding proteins. We as well as others previously have shown that Rheb is a… Expand
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Highly Cited
2007
Highly Cited
2007
Mammalian target of rapamycin (mTOR) functions in two distinct signaling complexes, mTORC1 and mTORC2. In response to insulin and… Expand
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Highly Cited
2003
Highly Cited
2003
The mammalian target of rapamycin (mTOR) controls multiple cellular functions in response to amino acids and growth factors, in… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND The mammalian target of rapamycin (mTOR) controls the translation machinery via activation of S6 kinases 1 and 2 (S6K1… Expand
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Highly Cited
1999
Highly Cited
1999
The rapamycin-sensitive TOR signalling pathway in Saccharomyces cerevisiae activates a cell-growth program in response to… Expand
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