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TNFSF9 protein

Known as: 4 1BB Ligand, 4-1BB Ligand [Chemical/Ingredient], CD137 Ligand 
A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract B07: Immunostimulatory gene therapy enhances PD-1 blockade antibody therapy in experimental lung cancer
This study aims to evaluate if immunostimulatory gene therapy is a good enhancer of checkpoint blockade therapy. Lung cancer is a… 
2017
2017
Abstract 3634: A novel tumor-targeted 4-1BB agonist and its combination with T-cell bispecific antibodies: an off-the-shelf cancer immunotherapy alternative to CAR T-cells
Immune cell costimulation via 4-1BB agonism has shown anti-tumor activity in the clinic and is an important element of next… 
2014
2014
SA-4-1BBL: A Novel Form of the 4-1BB Costimulatory Ligand as an Adjuvant Platform for the Development of Subunit Cancer Vaccines
Protein-based therapeutic subunit vaccines against cancer have proven efficacy in various preclinical models. The translation of… 
2013
2013
Multimeric forms of CD40 ligand (CD40L), 4-1BB ligand (4-1BBL), OX40 ligand (OX40L), CD27L/CD70, and other TNFSFs as tools for adoptive cell therapy
  • R. Kornbluth
  • Journal of Immunotherapy for Cancer
  • 2013
  • Corpus ID: 7819856
The TNF SuperFamily (TNFSF) of ligands include 19 molecules some of which play key roles in the immune system. All of these… 
2012
2012
Abrogation of Myeloid Derived Suppressor Cell-Like Inhibitory Activity of K562 Restores Antigen Presenting Cell Functions
Abstract 4118 The human leukemia cell line K562 represents an attractive platform for creating an artificial antigen presenting… 
2011
2011
Cross-linking of CD137 ligand modulates immune responses of thioglycollate-elicited mouse peritoneal macrophages
ObjectiveThe aim of this study was to investigate effects of CD137 ligand (CD137L)-mediated reverse signaling on cellular… 
2008
2008
Blockade of the 4-1BB pathway attenuates graft arterial disease in cardiac allografts.
4-1BB, a member of the tumor necrosis factor (TNF) receptor superfamily, binds the 4-1BB ligand (4-1BBL) and works as a… 
2004
2004
Shock Syndromes , and Have Lower IL-4 Resistant to Lipopolysaccharide-Induced NK / NKT Cell Numbers and Function , Are CD 137-Deficient Mice Have Reduced
C D137, a 30-kDa member of the TNF receptor superfam-ily, exists as both a monomer and a 55-kDa dimer on a major subset of mouse… 
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