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TNFSF9 protein

Known as: 4 1BB Ligand, 4-1BB Ligand [Chemical/Ingredient], CD137 Ligand 
A membrane bound member of the TNF superfamily that is expressed on activated B-LYMPHOCYTES; MACROPHAGES; and DENDRITIC CELLS. The ligand is specific… 
National Institutes of Health

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In BloodProcess of secretionagonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 541: An unbiased screen identifies a CD137xPD-L1 bispecific IgG1 antibody with unique T cell activation and binding properties
CD137 (4-1BB) is a transmembrane costimulatory receptor on T and NK cells that enhances adaptive immune responses and is a… 
Review
2015
Review
2015
Is CD137 Ligand (CD137L) Signaling a Fine Tuner of Immune Responses?
Now, it has been being accepted that reverse signaling through CD137 ligand (CD137L) plays an important role in vivo during… 
2014
2014
Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens.
2013
2013
Ex vivo expansion of natural killer cells using cryopreserved irradiated feeder cells.
Currently, feeder cells are γ-irradiated immediately before use for the ex vivo expansion of natural killer (NK) cells from human… 
2011
2011
Incorporation of 4-1BB ligand into an adenovirus vaccine vector increases the number of functional antigen-specific CD8 T cells and enhances the duration of protection against influenza-induced…
Highly Cited
2009
Highly Cited
2009
Endogenous 4-1BB Ligand Plays a Critical Role in Protection from Influenza-Induced Disease1
A critical issue during severe respiratory infection is whether it is the virus or the host response that does the most damage… 
2008
2008
Induction of Proliferation and Monocytic Differentiation of Human CD34+ Cells by CD137 Ligand Signaling
CD137 is a member of the tumor necrosis factor receptor family and is involved in the regulation of activation, proliferation… 
2006
2006
A signal through 4‐1BB ligand inhibits receptor for activation of nuclear factor‐κB ligand (RANKL)‐induced osteoclastogenesis by increasing interferon (IFN)‐beta production
2003
2003
A functional anti-human 4-1BB ligand monoclonal antibody that enhances proliferation of monocytes by reverse signaling of 4-1BBL.
4-1BB Ligand (4-1BBL), a transmembrane molecule, member of the tumor necrosis factor ligand superfamily, is an important… 
2003
2003
4-1BB (CD137) Differentially Regulates Murine In Vivo Protein- and Polysaccharide-Specific Immunoglobulin Isotype Responses to Streptococcus pneumoniae
ABSTRACT 4-1BB (CD137) is induced on activated CD4+ and CD8+ T cells and delivers a costimulatory signal upon binding the 4-1BB… 
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